Results 61 to 70 of about 458,433 (298)

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

open access: yesMolecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé   +7 more
wiley   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

open access: yesMolecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka   +10 more
wiley   +1 more source

Antibodies against Entamoeba histolytica in individuals with intestinal amoebiasis presenting cysts and/or trophozoites in the feces Anticorpos anti-Entamoeba histolylica em indivíduos com amebíase intestinal apresentando cistos e/ou trofozoitas nas fezes

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 1991
Serum samples were obtained from 154 individuals infected with Entamoeba histolytica (78 symptomatic and 76 asymptomatic). Twelve had trophozoites in the feces whereas 142 had only cysts.
Maria das Graças Carvalho   +2 more
doaj   +1 more source

Toxoplasma gondii Parasitophorous Vacuole Membrane-Associated Dense Granule Proteins Regulate Maturation of the Cyst Wall

open access: yesmSphere, 2020
After differentiation is triggered, the tachyzoite-stage Toxoplasma gondii parasitophorous vacuole membrane (PVM) has been hypothesized to transition into the cyst membrane that surrounds the cyst wall and encloses bradyzoites.
Rebekah B. Guevara   +2 more
doaj   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

open access: yesMolecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair   +17 more
wiley   +1 more source

Possibilities of Using an Expert System in the Diagnosis of Jaw Cysts

open access: yesČeská Stomatologie a Praktické Zubní Lékařství, 2013
Introduction: Expert systems are among the most successful applications of artificial intelligence. Since their own commercial introduction in the early 80's of the last century, they have undergone rapid develop-ment and now they are used in many fields
N. Mahdian   +3 more
doaj   +1 more source

Baker's Cyst

open access: yesActa Rheumatologica Scandinavica, 1965
SummaryTwenty-six patients with Baker's cysts have been observed in the period January 1963 to May 1964. Swelling, redness, tenderness and pain in the leg below the cyst was noticed in 11 patients. Seven of these had anti-coagulation treatment before admission.
openaire   +4 more sources

Time, the final frontier

open access: yesMolecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain   +3 more
wiley   +1 more source

Nodular Elastoidosis with Cysts and Acne: A Case Report

open access: yesClinical, Cosmetic and Investigational Dermatology, 2023
Shicheng Jiao,1,* Mu Niu,2,* Jie Yang2 1Jiao Shicheng Medical Beauty Clinic, Haikou, Hainan, People’s Republic of China; 2Department of Dermatology, The Fifth People’s Hospital of Hainan Province, Haikou, People’s Republic of China*These ...
Jiao S, Niu M, Yang J
doaj  

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