An Isoform-Specific RUNX1C-BTG2 Axis Governs AML Quiescence and Chemoresistance. [PDF]
Han C +20 more
europepmc +1 more source
A phase 2 study incorporating sorafenib into the chemotherapy for older adults with FLT3-mutated acute myeloid leukemia: CALGB 11001 [PDF]
Uy, Geoffrey L., Westervelt, Peter
core +1 more source
Inherited thrombocytopenia (IT) caused by germline variants in RUNX1, ETV6 or ANKRD26 carries a high risk of developing haematological malignancy. This study examined the clinical, platelet and molecular characteristics of 66 patients with these conditions, who carried 24 distinct genetic variants in the corresponding genes.
Ana Marín‐Quílez +34 more
wiley +1 more source
The synergistic effect of 2-deoxy-D-glucose and cytarabine on mitochondria of stem-like cells derived from KG1-a. [PDF]
Rezaei S +3 more
europepmc +1 more source
Methotrexate and cytarabine inhibit progression of human lymphoma in NOD/SCID mice carrying a mutant dihydrofolate reductase and cytidine deaminase fusion gene [PDF]
Tülin Budak-Alpdoǧan +5 more
openalex +1 more source
CD123‐targeting immunotherapeutic approaches in acute myeloid leukaemia
Summary Treatment of relapsed or refractory acute myeloid leukaemia (AML) has remained a significant challenge, with limited available targeted immunotherapies. CD123, or the interleukin‐3 (IL‐3) receptor, has long been known as a potential target expressed on AML blasts, and a range of different approaches to targeting CD123 have been trialled with ...
Alexandra Dreyzin +2 more
wiley +1 more source
Emphysematous Gastritis in the Setting of Stage Four Colon Cancer After Radiation Therapy and Ongoing Chemotherapy: A Case Report. [PDF]
Johnson RW +4 more
europepmc +1 more source
Summary Anthracycline‐containing chemotherapy is associated with cardiovascular diseases (CVDs). While knowledge regarding the extent of cardiotoxicity in adult patients with acute myeloid leukaemia (AML) is sparse, anthracyclines remain a key component in the treatment.
Rikke Hedegaard Jensen +10 more
wiley +1 more source
Real-world management of blastic plasmacytoid dendritic cell neoplasm at an academic center with a broad regional referral base. [PDF]
Krah NM +6 more
europepmc +1 more source
Synergistic effect of SU11248 with cytarabine or daunorubicin on FLT3 ITD–positive leukemic cells [PDF]
Kevin Yee +7 more
openalex +1 more source

