Results 231 to 240 of about 87,437 (368)

An Isoform-Specific RUNX1C-BTG2 Axis Governs AML Quiescence and Chemoresistance. [PDF]

open access: yesBlood Cancer Discov
Han C   +20 more
europepmc   +1 more source

Insights into the clinical, platelet and genetic landscape of inherited thrombocytopenia with malignancy risk

open access: yesBritish Journal of Haematology, Volume 207, Issue 4, Page 1565-1577, October 2025.
Inherited thrombocytopenia (IT) caused by germline variants in RUNX1, ETV6 or ANKRD26 carries a high risk of developing haematological malignancy. This study examined the clinical, platelet and molecular characteristics of 66 patients with these conditions, who carried 24 distinct genetic variants in the corresponding genes.
Ana Marín‐Quílez   +34 more
wiley   +1 more source

Methotrexate and cytarabine inhibit progression of human lymphoma in NOD/SCID mice carrying a mutant dihydrofolate reductase and cytidine deaminase fusion gene [PDF]

open access: hybrid, 2004
Tülin Budak-Alpdoǧan   +5 more
openalex   +1 more source

CD123‐targeting immunotherapeutic approaches in acute myeloid leukaemia

open access: yesBritish Journal of Haematology, Volume 207, Issue 4, Page 1178-1191, October 2025.
Summary Treatment of relapsed or refractory acute myeloid leukaemia (AML) has remained a significant challenge, with limited available targeted immunotherapies. CD123, or the interleukin‐3 (IL‐3) receptor, has long been known as a potential target expressed on AML blasts, and a range of different approaches to targeting CD123 have been trialled with ...
Alexandra Dreyzin   +2 more
wiley   +1 more source

Cardiotoxicity in patients with acute myeloid leukaemia following anthracycline‐containing chemotherapy: A population‐based matched cohort study

open access: yesBritish Journal of Haematology, Volume 207, Issue 4, Page 1416-1424, October 2025.
Summary Anthracycline‐containing chemotherapy is associated with cardiovascular diseases (CVDs). While knowledge regarding the extent of cardiotoxicity in adult patients with acute myeloid leukaemia (AML) is sparse, anthracyclines remain a key component in the treatment.
Rikke Hedegaard Jensen   +10 more
wiley   +1 more source

Synergistic effect of SU11248 with cytarabine or daunorubicin on FLT3 ITD–positive leukemic cells [PDF]

open access: bronze, 2004
Kevin Yee   +7 more
openalex   +1 more source

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