Results 311 to 320 of about 87,437 (368)
Some of the next articles are maybe not open access.

A Versatile Prodrug Strategy to In Situ Encapsulate Drugs in MOF Nanocarriers: A Case of Cytarabine‐IR820 Prodrug Encapsulated ZIF‐8 toward Chemo‐Photothermal Therapy

Advanced Functional Materials, 2018
Zeolitic imidazolate framework‐8 (ZIF‐8) is an attractive metal organic framework (MOF) in drug delivery. Strong interaction between drugs and ZIF‐8 is essential for high drug loadings through in situ construction of MOFs.
Zhonghao Li, Yuxia Luan
exaly   +2 more sources

Cytarabine ears – A side effect of cytarabine therapy

Journal of Oncology Pharmacy Practice, 2020
Cytarabine, a pyramidine analog, is used for treating various hematological malignancies such as acute leukemias and lymphomas. Side effects of cytarabine are dose dependent and include bone marrow suppression, fever, cerebellar toxicity, cardiomyopathy,
D. Doval   +4 more
semanticscholar   +4 more sources

Cytarabine

Journal of Pediatric Oncology Nursing, 1990
Cytarabine is effective in the treatment of leukemias and CNS disease when given SQ, IM, IV, or intrathecally. Research is continuing to investigate high-dose therapy with cytarabine.
D L, Betcher, N, Burnham
openaire   +2 more sources

Cytarabine and neurologic toxicity. [PDF]

open access: possibleJournal of Clinical Oncology, 1991
Cytarabine is an effective drug in the treatment of certain hematologic malignancies and its common toxicities are myelosuppression and gastrointestinal disturbance. In the past decade, neurotoxicity has been an increasingly recognized cytarabine effect. Intrathecal (IT) cytarabine may result in myelopathy that is incompletely reversible.
R B Weiss, G L Royer, W J Baker
openaire   +2 more sources

Deoxycytidine Kinase (DCK) Mutations in Human Acute Myeloid Leukemia Resistant to Cytarabine

Acta Haematologica, 2021
Resistance to cytarabine is an important cause of therapy failure in persons with acute myeloid leukemia (AML). Deoxycytidine kinase, encoded by DCK, catalyzes phosphorylation of cytarabine to cytarabine monophosphate, a necessary step for eventual ...
Biao Wu   +10 more
semanticscholar   +1 more source

Bexarotine and Cytarabine, Liposomal [PDF]

open access: possibleHospital Pharmacy, 2000
The increasing complexity of cancer chemotherapy makes it mandatory that pharmacists be familiar with these highly toxic agents. This column examines issues related to the preparation, dispensing, and administration of cancer chemotherapy and reviews agents, both commercially available and investigational, used to treat malignant diseases.
Dominic A. Solimando, J. Aubrey Waddell
openaire   +1 more source

Safety and feasibility of outpatient high-dose cytarabine and intermediate-dose cytarabine for consolidation therapy in acute myeloid leukemia

Journal of Oncology Pharmacy Practice, 2021
Introduction The standard of care consolidation therapy for acute myeloid leukemia is high-dose cytarabine or intermediate-dose cytarabine, which are traditionally given inpatient.
Wenhui Li   +4 more
semanticscholar   +1 more source

Development and application of a rapid and sensitive liquid chromatography-mass spectrometry method for simultaneous analysis of cytarabine, cytarabine monophosphate, cytarabine diphosphate and cytarabine triphosphate in the cytosol and nucleus

Journal of Pharmaceutical and Biomedical Analysis, 2022
In this study, a sensitive and rapid ultra-high-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) method was developed for the simultaneous analysis of cytarabine (ara-C), cytarabine monophosphate (ara-CMP), cytarabine diphosphate (ara-CDP) and cytarabine triphosphate (ara-CTP) in the cytosol and nucleus.
Shenjia, Huang   +5 more
openaire   +2 more sources

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