Results 51 to 60 of about 87,437 (368)

Sodium N-lauryl amino acids derived from silk protein can form catanionic aggregates with cytarabine as novel anti-tumor drug delivery systems

Drug Delivery, 2020
A sodium N-lauryl amino acids (shortly silk sericin surfactant, SSS) is synthesized with lauryl chloride and sericin amino acids recovered from silk industrial waste. The purpose of this study is to explore whether the sericin surfactant can be used as a
Meng Zhang, Shu-Xiang Zhao, Biao Ding, Yu-Qing Zhang   +3 more
doaj   +1 more source

Effectiveness of the Initial Escalation of Immunochemotherapy in Patients with High Risk MALT-Lymphoma: Pilot Study Results [PDF]

Клиническая онкогематология, 2018
Background. MALT-lymphoma is usually characterized with an indolent course. The factors underlying the effectiveness of the standard chemotherapy in patients with MALT-lymphomas include MALT-IPI risk group and a high SUVmax according to the results of ...
AK Smol’yaninova, NG Gabeeva, SA Tatarnikova, AV Belyaeva, AM Kovrigina, EG Gemdzhyan, EE Zvonkov   +6 more
doaj   +1 more source

Cytarabine-Induced Corneal Toxicity: Clinical Features and Relief of Symptoms with Loteprednol Etabonate 0.5% in Two Patients

Türk Oftalmoloji Dergisi, 2021
We report two patients who developed toxic keratopathy following high-dose cytarabine chemotherapy and whose symptoms resolved following topical loteprednol etabonate 0.5% treatment.
Gökçen Özcan, Ömür Özlenen Uçakhan   +1 more
doaj   +1 more source

B/T Mixed Phenotype Acute Leukaemia Harbouring <i>NUP98::BPTF</i> Fusion. [PDF]

EJHaem
ABSTRACT Background NUP98::BPTF rearranged (r) leukaemia is rare with only five reported cases, including acute myeloid leukemia and T‐lymphoblastic leukemia (T‐ALL). Results Herein, we report a case of NUP98::BPTF‐r mixed phenotype acute leukemia (MPAL), B/T with T‐lineage‐predominance in a 15‐year‐old female.
Nguyen VT, Han L, Xu J, Cantu M, Fuda F, John S, Slone T, Chen W.   +7 more
europepmc   +2 more sources

BL‐8040 CXCR4 antagonist is safe and demonstrates antileukemic activity in combination with cytarabine for the treatment of relapsed/refractory acute myelogenous leukemia: An open‐label safety and efficacy phase 2a study

Cancer, 2020
CXCR4 mediates the retention and survival of acute myelogenous leukemia blasts in bone marrow and contributes to their resistance to chemotherapy. The authors evaluated a combination of the high‐affinity CXCR4 antagonist BL‐8040 with high‐dose cytarabine
G. Borthakur, Y. Ofran, M. Tallman, J. Foran, G. Uy, J. Dipersio, M. Showel, A. Shimoni, A. Nagler, J. Rowe, J. Altman, Michal Abraham, A. Peled, Stephen M. Shaw, O. Bohana‐Kashtan, E. Sorani, Y. Pereg, A. Foley-Comer, G. Oberkovitz, Tzipi Lustig, Irit Glicko-Kabir, A. Aharon, A. Vainstein-Haras, S. Kadosh, E. Samara, Ahmed Al-rawi, N. Pemmaraju, C. Bueso-Ramos, J. Cortes, M. Andreeff   +29 more
semanticscholar   +1 more source

Platelet-derived microparticles enhance Ara-C-induced cell death in acute lymphoblastic leukemia (Nalm-6) [PDF]

BioImpacts
Introduction: The current understanding highlights the intricate relationship between leukemic cells and their microenvironment, emphasizing the significant impact of environmental factors on chemotherapy resistance or sensitivity.
Fariba Nikravesh, Hossein Arezoomand, Roohollah h Mirzaee Khalilabadi, Maryam Nooshadokht, Hajar Mardani Valandani   +4 more
doaj   +1 more source

Prognostication refinement in NPM1‐mutated acute myeloid leukemia stratified by FLT3‐ITD status with different induction doses of cytarabine

Cancer Medicine, 2023
Objective We aimed to retrospectively discern the heterogeneity of outcomes from clinicopathological characteristics and next‐generation sequencing (NGS) data in adult patients with NPM1‐mutated (NPM1mut) acute myeloid leukemia (AML) induced with ...
Biao Wang, Xiaoying Hua, Jihong Zhang, Weiying Gu, Haiqian Li   +4 more
doaj   +1 more source

Impact of IFN lambda 3/4 single nucleotide polymorphisms on the cytomegalovirus reactivation in autologous stem cell transplant patients [PDF]

, 2018
Cytomegalovirus (CMV) infection represents one of the main cause mortality after Stem Cell Transplantation. Recently, a protective effect of the T allele of rs12979860 IL28B Single Nucleotide Polymorphisms (SNPs) against CMV infection in the allogenic ...
Angeletti, S, Annibali, O, Avvisati, G, Cantonetti, M, Circhetta, E, Franceschini, L, Piccioni, L, Riva, E., Rizzo, E, Sarlo, C, Scagnolari, C, Statzu, M, Tirindelli, Mc, Tomarchio, V   +13 more
core   +1 more source

Mantle Zone Cell Lymphomas. New Opportunities for Diagnosis and Treatment (Epidemiological Research)

Креативная хирургия и онкология, 2020
Introduction. Mantle cell lymphoma is a rare type of B-cell non-Hodgkin lymphoma. According to statistics the incidence of this disorder amounts to 2-3 per 100,000 people; this is about 6% of all non-Hodgkin lymphomas.
E. I. Kankumasheva, Ch. Kh. Valiakhmetova   +1 more
doaj   +1 more source

Physiological and histological effects of apigenin and luteolin on Cytarabine injected rats

مجلة بغداد للعلوم
         The present study was undertaken to study the effect of apigenin and luteolin on physiological and histological changes in rats treated with cytarabine drugs.
Ghada A. Taqa, Omar N. Sultan
doaj   +1 more source