Deficiency of Aging‐Related Gene Chitinase‐Like 4 Impairs Olfactory Epithelium Homeostasis
Deficiency of Chil4 impairs OE homeostasis through loss of sustentacular cells and a specific type of immature sensory neuron, cell cycle arrest in globose basal cells, and inflammatory activation in microglia‐like cells. ABSTRACT Mammalian olfactory epithelium (OE) undergoes consistent self‐renewal throughout life.
Tingting Wu+7 more
wiley +1 more source
Scientists studied how microorganisms in permafrost‐affected peatland ecosystems process organic matter to predict greenhouse gas emissions. Using advanced molecular techniques, they discovered that the chemical quality of organic compounds determines whether microbes produce more or less methane and other greenhouse gases. This research provides a new
John A. Bouranis+8 more
wiley +1 more source
ABSTRACT Colorectal cancer (CRC) ranks among the primary causes of cancer deaths worldwide. Cholesterol metabolism, tightly regulated through biosynthesis, uptake, efflux and conversion, plays a crucial role in CRC development and progression. Dysregulated cholesterol metabolism in cancer cells alters the tumour microenvironment (TME), promoting tumour
Chunyu Zhang+4 more
wiley +1 more source
Non‐coding RNAs in plant stress responses: molecular insights and agricultural applications
Summary Non‐coding RNAs (ncRNAs) have emerged as crucial regulators in plant responses to environmental stress, orchestrating complex networks that finetune gene expression under both abiotic and biotic challenges. To elucidate this intricate ncRNA crosstalk, this review comprehensively summarizes recent advances in understanding the mechanisms of key ...
Xiaotong Chen+3 more
wiley +1 more source
Oxidative Stress Response of Liver Cell Culture in Atlantic Salmon Challenged Under Two Antibiotics: Oxytetracycline and Florfenicol. [PDF]
Vargas-Chacoff L+4 more
europepmc +1 more source
Reactivity of canonical bacterial cytochrome <i>c</i> peroxidases: insights into the electronic structure of compound I. [PDF]
Hewitt P, Hendrich MP, Elliott SJ.
europepmc +1 more source
Dietary Gluten-Free Regimen Does Not Affect the Suppression of the Inflammatory Response in the Arachidonic Acid Cascade in Hashimoto's Disease. [PDF]
Szczuko M+7 more
europepmc +1 more source
Using of transporter proteins to improve the uptake efficiency of hydrophobic compounds by Escherichia coli: a coordinated synthesis of START protein and P450scc system proteins to enhance cholesterol biotransformation. [PDF]
Zamalutdinova SV+7 more
europepmc +1 more source
The Regulatory Role of Exogenous Carnitine Applications in Lipid Metabolism, Mitochondrial Respiration, and Germination in Maize Seeds (<i>Zea mays</i> L.). [PDF]
Turk H, Genisel M, Dumlupinar R.
europepmc +1 more source