Results 261 to 270 of about 203,240 (311)

Deficiency of Aging‐Related Gene Chitinase‐Like 4 Impairs Olfactory Epithelium Homeostasis

open access: yesCell Proliferation, Volume 58, Issue 8, August 2025.
Deficiency of Chil4 impairs OE homeostasis through loss of sustentacular cells and a specific type of immature sensory neuron, cell cycle arrest in globose basal cells, and inflammatory activation in microglia‐like cells. ABSTRACT Mammalian olfactory epithelium (OE) undergoes consistent self‐renewal throughout life.
Tingting Wu   +7 more
wiley   +1 more source

Metabolic Redox Coupling Controls Methane Production in Permafrost‐Affected Peatlands Through Organic Matter Quality‐Dependent Energy Allocation

open access: yesGlobal Change Biology, Volume 31, Issue 8, August 2025.
Scientists studied how microorganisms in permafrost‐affected peatland ecosystems process organic matter to predict greenhouse gas emissions. Using advanced molecular techniques, they discovered that the chemical quality of organic compounds determines whether microbes produce more or less methane and other greenhouse gases. This research provides a new
John A. Bouranis   +8 more
wiley   +1 more source

Dysregulated Cholesterol Metabolism and Its Impact on the Tumour Immune Response in Colorectal Cancer

open access: yesJournal of Cellular and Molecular Medicine, Volume 29, Issue 15, August 2025.
ABSTRACT Colorectal cancer (CRC) ranks among the primary causes of cancer deaths worldwide. Cholesterol metabolism, tightly regulated through biosynthesis, uptake, efflux and conversion, plays a crucial role in CRC development and progression. Dysregulated cholesterol metabolism in cancer cells alters the tumour microenvironment (TME), promoting tumour
Chunyu Zhang   +4 more
wiley   +1 more source

Non‐coding RNAs in plant stress responses: molecular insights and agricultural applications

open access: yesPlant Biotechnology Journal, Volume 23, Issue 8, Page 3195-3233, August 2025.
Summary Non‐coding RNAs (ncRNAs) have emerged as crucial regulators in plant responses to environmental stress, orchestrating complex networks that finetune gene expression under both abiotic and biotic challenges. To elucidate this intricate ncRNA crosstalk, this review comprehensively summarizes recent advances in understanding the mechanisms of key ...
Xiaotong Chen   +3 more
wiley   +1 more source

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