Results 81 to 90 of about 5,044 (130)

Variable expression of hepatic genes in different liver tumor cell lines: conclusions for drug testing. [PDF]

Front Cell Dev Biol
Wisniewska MJ, Wencel A, Jakubowska M, Motyl JA, Dudek K, Burzynska B, Pijanowska DG, Pluta KD.   +7 more
europepmc   +1 more source

The role of cytochrome P450 genetic variants in pesticide metabolism and the risk of child neurodevelopment: a systematic review. [PDF]

Front Pediatr
Chilipweli PM, Kidenya BR, Nyanza EC, Ngowi AV, Manji K.   +4 more
europepmc   +1 more source

Impact of variation in CYP3A and CYP2C8 on tucatinib metabolic clearance in human liver microsomes. [PDF]

Drug Metab Dispos
Latham BD, Montazeri P, Lobo LF, Fallon JK, Jackson KD.   +4 more
europepmc   +1 more source

Development and Verification of a Physiologically Based Pharmacokinetic Model of Furmonertinib and Its Main Metabolite for Drug-Drug Interaction Predictions. [PDF]

CPT Pharmacometrics Syst Pharmacol
Wu Y, Loer HLH, Zhang Y, Zhong D, Jiang Y, Hu J, Fuhr U, Lehr T, Diao X.   +8 more
europepmc   +1 more source

Influence of CYP2C8 Polymorphism on the Exposure to Chloroquine in Patients with Malaria by <i>Plasmodium vivax</i>-A Preliminary Study. [PDF]

Int J Environ Res Public Health
Pereira de Sena LW, Fuzii HT, Villanova FE, Nunes Cardoso Mello AG, de Sena MPM, Dias Ferreira MV, Fernandes Vieira JL.   +6 more
europepmc   +1 more source

A functional ancestry-linked regulatory haplotype influences CYP2D6 expression. [PDF]

Pharmacogenomics J
McCoy M.
europepmc   +1 more source

Physiologically Based Pharmacokinetic Modeling to Assess Perpetrator and Victim Cytochrome P450 2C Induction Risk. [PDF]

Pharmaceutics
Slavsky M, Karve AS, Hariparsad N.
europepmc   +1 more source

Transcription factors of the Nuclear Factor I (NFI) family control hepatocyte differentiation and cytochrome P450 activity in human liver.

Pharmacol Res
Klein K, Burk O, Tremmel R, Buettner FA, Kaestle L, Schroth W, Muerdter TE, Eccles D, Schmidt AC, Nieß H, Zanger UM, Schwab M, Lauschke VM.   +12 more
europepmc   +1 more source

Dietary Modulation of CYP3A4 and Its Impact on Statins and Antidiabetic Drugs: A Narrative Review. [PDF]

Pharmaceuticals (Basel)
Hernández-Lorca M, Timón IM, Ballester P, Henarejos-Escudero P, García-Muñoz AM, Victoria-Montesinos D, Barcina-Pérez P.   +6 more
europepmc   +1 more source

Humanization of Drug Metabolism in the <i>Plasmodium berghei</i> Mouse Model for Antimalarial Drug Discovery. [PDF]

ACS Infect Dis
MacLeod AK, Merino C, Viera-Morilla S, Frame L, Tavendale A, Duncan C, Ferguson L, Pinto EG, Simeons FRC, Gomez-Jimenez V, García AB, Riley J, Shishikura Y, Martínez-Martínez MS, Wolf CR, Read KD.   +15 more
europepmc   +1 more source