Results 231 to 240 of about 283,519 (305)

Use of a cytochrome P450 humanised mouse model to refine schistosomiasis drug discovery

Davey SD, Forde-Thomas JE, Hulme BJ, Lees K, Costain AH, Evans M, Rinaldi G, Frame L, Stojanovski L, Simeons FRC, Tavendale A, Kenneth MacLeod A, Pichon R, Lee Y, Polak O, Chalmers IW, Dankwa B, Odhiambo BK, Guimaraes VH, Hegarty M, Swain MT, Aubrey W, Caldwell N, MacDonald AS, Gilbert IH, Baragaña B, Read KD, Hoffmann KF.   +27 more
europepmc   +1 more source

Cytochrome P450-Induced Backbone Rearrangements in Terpene Biosynthesis of Plants. [PDF]

Molecules
Frey M, Jochimsen CM, Degenhardt J.
europepmc   +1 more source

Thirty years of glyphosate‐resistant crops and weeds: Current situation and future prospects

Pest Management Science, EarlyView.
Since 1996, when the first glyphosate‐resistant crop was commercialized and the first resistant weed was reported, resistance has expanded globally. This review analyzes emergence patterns across weed species, crops, regions, resistance mechanisms, and herbicides.
Ricardo Alcántara‐de la Cruz, Yure Marin Guidi, Mariana Ramirez‐Castillo, Fernando Storniolo Adegas, Caio Antonio Carbonari, Edivaldo Domingues Velini, Rafael De Prado, Stephen O. Duke   +7 more
wiley   +1 more source

Steroid Hydroxylation by Mutant Cytochrome P450 BM3-LG23 Using Two Expression Chassis. [PDF]

Int J Mol Sci
Poshekhontseva V, Nikolaeva V, Shutov A, Kazantsev A, Sazonova O, Strizhov N, Donova M.   +6 more
europepmc   +1 more source

RNA interference in crop protection: opportunities and challenges during the transition to commercialization

Pest Management Science, EarlyView.
RNA interference (RNAi) technologies, host‐induced gene silencing (HIGS) and spray‐induced gene silencing (SIGS), potentially offer sustainable crop protection. However, efficacy, costs, regulatory clarity, and socio‐environmental impacts require further evaluation for broader use.
Elisabetta Sergi, Anna Narduzzo, Alessandra Di Canito, Francesco Favaretto, Luca Nerva, Walter Chitarra, Lucia Bologna, Jacopo Bacenetti, Giuliana Maddalena, Simona Masiero, Ileana Vigentini, Gabriella De Lorenzis, Silvia Laura Toffolatti   +12 more
wiley   +1 more source

The Activation of Cytochrome P450 2C9 Is Facilitated by the Coenzyme Forms of Vitamin B2. [PDF]

Molecules
Koroleva PI, Kuzikov AV, Gilep AA, Ivanov SV, Archakov AI, Shumyantseva VV.   +5 more
europepmc   +1 more source

Analysis of glutamine synthetase target‐site mutations and their role in endowing glufosinate‐ammonium resistance

Pest Management Science, EarlyView.
GS2.2 G255D mutation conferred enzyme‐level glufosinate insensitivity but no whole‐plant resistance, showing trade‐offs between catalytic function and herbicide binding and providing a baseline for future studies on target‐site glufosinate resistance.
Aimone Porri, Susee Sudhakar, Matheus M Noguera, Michael Betz, Jens Lerchl, Franck E Dayan, Ingo Meiners, Tino Caldarelli, Jason Norsworthy   +8 more
wiley   +1 more source

Cytochrome P450-derived metabolites of docosahexaenoic acid or arachidonic acid enhance contractility of cultured rat cardiomyocytes: a pilot study. [PDF]

J Artif Organs
Kawakami H, Sato D, Sazuka M, Tsuchida S, Nishina A, Nakamura T, Kusunoki M, Tsutsumi K, Feng Z.   +8 more
europepmc   +1 more source

Distribution and frequency of Vkorc1 polymorphisms in house mice and Norway rats in the northeastern United States

Pest Management Science, EarlyView.
This study assesses the distribution and frequency of Vkorc1 polymorphisms in house mice and Norway rats in northeastern USA. House mice showed higher frequency of Vkorc1 mutations than Norway rats. The A32V and Y139F mutations are first reported in mice, and the L128V is newly reported in Norway rats.
Jin‐Jia Yu, Alvaro Toledo, Adrienne E Kasprowicz, Megan V Phifer‐Rixey, Xiaodan Pan, Babatunji Daramola, Changlu Wang   +6 more
wiley   +1 more source

Structural basis for substrate-dependent allostery in oxygen activation by a cytochrome P450 enzyme revealed by analysis at different temperatures. [PDF]

Chem Sci
Podgorski MN, McDougal DP, Campbell EC, Bruning JB, Bell SG.   +4 more
europepmc   +1 more source