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Spectroscopic Interrogation of Thiolate Hydrogen Bonding in the CO Sensor Protein CooA: Implications for Thiolate Ligation Stability and Cytochrome P450 Function. [PDF]
Weaver BR+4 more
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Cytochrome P450 3A gene family and medication in childhood nephrotic syndrome: An update. [PDF]
Kochuthakidiyel Suresh P+5 more
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Correction for Ravanfar et al., Tryptophan extends the life of cytochrome P450. [PDF]
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Structure and Chemistry of Cytochrome P450
ChemInform, 2005AbstractFor Abstract see ChemInform Abstract in Full Text.
Denisov, I.+3 more
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Cytochrome P450 Structure, Function and Clinical Significance: A Review.
Current Drug Targets, 2018BACKGROUND The cytochrome P450 (CYP) enzymes are membrane-bound hemoproteins that play a pivotal role in the detoxification of xenobiotics, cellular metabolism and homeostasis.
P. Manikandan, S. Nagini
semanticscholar +1 more source
Cytochrome P450s and chemoprevention
Biochemical Society Transactions, 2000The cytochrome P450 mono-oxygenase system represents a major defence against chemical challenge from the environment, constituting part of an adaptive response mounted by an organism following exposure to harmful agents. Cytochrome P450s are also able to catalyse the activation of compounds to toxic products, and participate in a variety of essential ...
Henderson, C J, Sahraouei, A, Wolf, C R
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Cytochrome P450: genotype to phenotype
Xenobiotica; the fate of foreign compounds in biological systems, 2019The cytochromes P450 comprise a family of enzymes that are responsible for around three-quarters of all drug metabolism reactions that occur in human populations. Many isoforms of cytochrome P450 exist but most reactions are undertaken by CYP2C9, CYP2C19,
R. Waring
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