Results 61 to 70 of about 44,893 (265)

Head and neck cancer: searching for genomic and epigenetic biomarkers in body fluids – the state of art

Molecular Cytogenetics, 2019
Head and neck squamous cell carcinoma (HNSCC) affects multiple sites of the upper aerodigestive tract and exhibited high incidence and mortality worldwide, being frequently diagnosed at advanced stage.
Ilda Patrícia Ribeiro, Joana Barbosa de Melo, Isabel Marques Carreira   +2 more
doaj   +1 more source

Cytogenetics of hepatoblastoma

Frontiers in Bioscience, 2012
The cytogenetics of hepatoblastoma demonstrate recurring events which include whole chromosome trisomies, most commonly trisomy of chromosome 2, 8, or 10. In addition, unbalanced translocations involving a breakpoint on the proximal short arm of chromosome 1 are observed which result in a duplication of the long arm of chromosome 1q.
openaire   +2 more sources

Semi‐mechanistic population PK/PD model to aid clinical understanding of myelodysplastic syndromes following treatment with Venetoclax and Azacitidine

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 448-459, March 2025.
Abstract Myelodysplastic syndromes (MDS) represent a group of bone marrow disorders involving cytopenias, hypercellular bone marrow, and dysplastic hematopoietic progenitors. MDS remains a challenge to treat due to the complex interplay between disease‐induced and treatment‐related cytopenias.
Neha Thakre, Corinna Maier, Jiuhong Zha, Benjamin Engelhardt, Johannes E. Wolff, Sven Mensing   +5 more
wiley   +1 more source

CYTOGENETICS OF SPECIATION

Australian Journal of Entomology, 1970
iThe essence of speciation lies in the origin of genetic isolating mechanisms. Argument has raged as to whether the primary isolating mechanisms which initiate specific divergence operate at the pre‐mating or post‐mating level and whether complete geographic isolation necessarily precedes divergence.
openaire   +2 more sources

Micronuclei and Other Nuclear Abnormalities in Patella Limpet as Biomarkers of Cytogenotoxicity in Recreational Port Waters

Environmental Toxicology, EarlyView.
ABSTRACT Over the past decades, the growth in human population and economic activities has led to an increase in maritime traffic. This rise puts additional pressure on marine environments, vessel fuel spills being considered to have a major impact on the ecosystem.
Carlos Valiente‐Diaz, Eva Garcia‐Vazquez, Verónica Soto‐López   +2 more
wiley   +1 more source

Genes commonly deleted in childhood B-cell precursor acute lymphoblastic leukemia: association with cytogenetics and clinical features

Haematologica, 2013
In childhood B-cell precursor acute lymphoblastic leukemia, cytogenetics is important in diagnosis and as an indicator of response to therapy, thus playing a key role in risk stratification of patients for treatment.
Claire J. Schwab, Lucy Chilton, Heather Morrison, Lisa Jones, Halima Al-Shehhi, Amy Erhorn, Lisa J. Russell, Anthony V. Moorman, Christine J. Harrison   +8 more
doaj   +1 more source

Cytogenotoxic Effects of Fluopyram in Allium cepa Root Cells Involving Microtubule Disruption

Environmental Toxicology, EarlyView.
ABSTRACT Fluopyram is a next‐generation fungicide widely used in agriculture; however, its persistence in soils and mobility toward aquatic systems have raised concerns regarding potential ecotoxicological risks. This study evaluated the cytogenotoxic effects of a commercial fluopyram‐based pesticide formulation on Allium cepa root meristem cells ...
Carlos Filipe Camilo‐Cotrim, Natanael Alves da Silva, Gabriela Gomes Lima, Igor Rodrigues Vasconcelos, Luciana Souza Ondei, Elisa Flávia Luiz Cardoso Bailão, Antônio Sérgio Nakao de Aguiar, Marcelino Benvindo‐Souza, Leonardo Luiz Borges, Virgínia Damin, Luciane Madureira Almeida   +10 more
wiley   +1 more source

Impact of brief telehealth interventions on parental stress and challenging behaviors of children with fragile X syndrome

Orphanet Journal of Rare Diseases
Background Fragile X syndrome (FXS) is the most common cause of inherited intellectual disability (ID) with comorbid autism and several support requirements.
María Francisca Miranda, Víctor Faundes, María Angélica Alliende, Lorena Santa María   +3 more
doaj   +1 more source

Nanopharmaceutical Approach for Enhanced Anti-cancer Activity of Betulinic Acid in Lung-cancer Treatment via Activation of PARP: Interaction with DNA as a Target -Anti-cancer Potential of Nano-betulinic Acid in Lung Cancer-

Journal of Pharmacopuncture, 2016
Objectives: This study examined the relative efficacies of a derivative of betulinic acid (dBA) and its poly (lactide- co-glycolide) (PLGA) nano-encapsulated form in A549 lung cancer cells in vivo and in co-mutagen [sodium arsenite (SA) + benzo]undefined[
Jayeeta Das, Asmita Samadder, Sreemanti Das, Avijit Paul, Anisur Rahman Khuda-Bukhsh   +4 more
doaj   +1 more source

Cytogenotoxic and Molecular Assessment of Pyrethrins on Non‐Target Allium cepa Roots

Environmental Toxicology, EarlyView.
ABSTRACT The pyrethrins, which form a part of naturally occurring insecticidal chemicals derived from chrysanthemum flowers, not only provide rapid knockdown of a broad spectrum of insect pests but are also widely used in integrated pest management due to a generally favorable safety profile, largely attributed to low mammalian toxicity.
Yudum Yeltekin Uğur, Rahsan Ilikci‐Sagkan, Recep Liman   +2 more
wiley   +1 more source