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Diagnosis of Cytomegalovirus Infection

Clinical Infectious Diseases, 1988
Diagnostic procedures for documenting cytomegalovirus (CMV) infection include culture, cytology, serology, and the detection of CMV antigens and/or nucleic acids within infected tissues. Each procedure is useful, but each has specific pitfalls. A positive urine, blood, or genital culture confirms CMV infection but does not prove that CMV is causing a ...
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Congenital cytomegalovirus infections

Seminars in Fetal and Neonatal Medicine, 2007
Congenital cytomegalovirus (CMV) infection is one of the most common viral causes of congenital infections in high resource countries and a leading cause of hearing loss as well as an important contributor to neurodevelopmental disabilities in children.
Gunilla, Malm, Mona-Lisa, Engman
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Congenital cytomegalovirus infection

American Journal of Obstetrics and Gynecology, 1969
Abstract Five cases of congenital cytomegalovirus infection are presented. In the three cases studied by virologic and immunologic techniques, it was demonstrated that complement-fixing antibody titers are low in contrast to the postnatally acquired infection.
R J, Hildebrandt, G R, Monif
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Cytomegalovirus infections and the skin

Journal of the American Academy of Dermatology, 1988
Cytomegalovirus has received renewed recognition as a pathogen in recent years. This article emphasizes the cutaneous manifestations of cytomegalovirus infection.
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Congenital cytomegalovirus infection

Seminars in Perinatology, 2018
Each year, thousands of children are born with or develop permanent disabilities such as hearing loss, vision loss, motor and cognitive deficits from congenital CMV infection (cCMV). However, awareness of cCMV and its associated sequelae is very low in pregnant women and healthcare providers.
Karen B, Fowler, Suresh B, Boppana
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Cytomegalovirus infection in pregnancy

International Journal of Gynecology & Obstetrics, 2002
AbstractObjectives: To investigate the effects of intrauterine human cytomegalovirus (HCMV) infection on pregnancy outcomes and infant development. Methods: The study group consisted of the HCMV‐IgM‐positive offspring of 75 pregnant women, and a control group of the non‐infected offspring of 73 pregnant women.
L Z, Wen   +5 more
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Epidemiology of Cytomegalovirus Infections

Clinical Infectious Diseases, 1990
The determinants of cytomegalovirus (CMV) infection and disease can now be understood from studies of newborns, recipients of organ or bone marrow transplants, subjects infected with human immunodeficiency virus, and recipients of blood transfusions. CMV is transmitted to the neonate transplacentally, by passage through a contaminated birth canal, or ...
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Treatment of Cytomegalovirus Infection

Clinics in Laboratory Medicine, 1987
CMV infection is a major cause of morbidity and mortality in the immune compromised host. Ganciclovir and phosphonoformate have in vitro and in vivo activity against human CMV, and controlled trials of both these drugs in immunocompromised patients have suggested their efficacy.
E C, Reed, J D, Meyers
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Congenital cytomegalovirus infection

European Journal of Obstetrics & Gynecology and Reproductive Biology, 1995
Congenital cytomegalovirus is the most common viral infection affecting approximately 1% of newborns. The virus can be transmitted to the fetus during both primary and recurrent infection. Although most of the infants are asymptomatic at birth, up to 15% develop late complications.
Y, Daniel   +3 more
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Cytomegalovirus infection in pregnancy

Journal of Virological Methods, 1987
Cytomegalovirus (CMV) is the most common agent of prenatal (peri- and early postnatal) infection of the newborn with an incidence of 0.2-2.0% (5-10%) depending on the socio-economic status. Only one out of 20 congenitally CMV-infected newborns shows serious symptoms. Another two may reveal mental retardation and other significant handicaps in later age.
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