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Diagnosis of Cytomegalovirus Infection

Clinical Infectious Diseases, 1988
Diagnostic procedures for documenting cytomegalovirus (CMV) infection include culture, cytology, serology, and the detection of CMV antigens and/or nucleic acids within infected tissues. Each procedure is useful, but each has specific pitfalls. A positive urine, blood, or genital culture confirms CMV infection but does not prove that CMV is causing a ...
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Cytomegalovirus infections and the skin

Journal of the American Academy of Dermatology, 1988
Cytomegalovirus has received renewed recognition as a pathogen in recent years. This article emphasizes the cutaneous manifestations of cytomegalovirus infection.
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Cytomegalovirus infection in pregnancy

International Journal of Gynecology & Obstetrics, 2002
AbstractObjectives: To investigate the effects of intrauterine human cytomegalovirus (HCMV) infection on pregnancy outcomes and infant development. Methods: The study group consisted of the HCMV‐IgM‐positive offspring of 75 pregnant women, and a control group of the non‐infected offspring of 73 pregnant women.
L Z, Wen   +5 more
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Congenital cytomegalovirus infection

European Journal of Obstetrics & Gynecology and Reproductive Biology, 1995
Congenital cytomegalovirus is the most common viral infection affecting approximately 1% of newborns. The virus can be transmitted to the fetus during both primary and recurrent infection. Although most of the infants are asymptomatic at birth, up to 15% develop late complications.
Y, Daniel   +3 more
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Cytomegalovirus infection in pregnancy

Journal of Virological Methods, 1987
Cytomegalovirus (CMV) is the most common agent of prenatal (peri- and early postnatal) infection of the newborn with an incidence of 0.2-2.0% (5-10%) depending on the socio-economic status. Only one out of 20 congenitally CMV-infected newborns shows serious symptoms. Another two may reveal mental retardation and other significant handicaps in later age.
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Posttransfusion Cytomegalovirus Infections

Pediatrics, 1982
Although cytomegalovirus (CMV) infection has been recognized as a potential hazard of blood transfusion since 1966,1 few transfusion services provide blood components that have been selected specifically for low risk of infectivity with CMV. The objective of this commentary is to provide a review of the epidemiology of posttransfusion CMV infections ...
S G, Sandler, F C, Grumet
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Congenital cytomegalovirus infection

2014
Congenital cytomegalovirus (CMV) infection, the most common congenital viral infection worldwide, occurs in approximately 1% of infants. Most congenitally infected infants have no long-term sequelae related to CMV infection. Approximately 10% have sensorineural hearing loss or neurologic deficits, including cerebral palsy, epilepsy, and cognitive ...
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Diagnosis of cytomegalovirus infection

Journal of Antimicrobial Chemotherapy, 1989
CMV is an important pathogen for immunocompromised patients. Since such individuals cannot be relied upon to mount appropriate immune responses promptly, methods for detecting virus must be used for diagnosis. Conventional virus isolation is slow and the sensitivity and specificity of a more rapid method using monoclonal antibodies are described. Other
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Epidemiology of Cytomegalovirus Infections

Clinical Infectious Diseases, 1990
The determinants of cytomegalovirus (CMV) infection and disease can now be understood from studies of newborns, recipients of organ or bone marrow transplants, subjects infected with human immunodeficiency virus, and recipients of blood transfusions. CMV is transmitted to the neonate transplacentally, by passage through a contaminated birth canal, or ...
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Chronic cytomegalovirus infection

Journal of Virological Methods, 1988
Cytomegalovirus infects about 60% of persons in developed countries and may cause significant disease in immunosuppressed patients. Serology has no role in the diagnosis of CMV disease in such patients yet detection of the virus in diseased parts of the body can be used to monitor the course of disease and antiviral measures.
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