Results 21 to 30 of about 197,216 (310)

Failure in generating hemopoietic stem cells is the primary cause of death from cytomegalovirus disease in the immunocompromised host [PDF]

, 1988
We have shown in a murine model system for cytomegalovirus (CMV) disease in the immunocompromised host that CMV infection interferes with the earliest detectable step in hemopoiesis, the generation of the stem cell CFU-S-I, and thereby prevents the ...
Busch, Friedrich W., Bühring, Hans-Jörg, Koszinowski, Ulrich H., Mutter, Wolfgang, Reddehase, Matthias J.   +4 more
core   +2 more sources

Perinatal Cytomegalovirus Infection

Current Treatment Options in Pediatrics, 2022
There have been recent advances in the field of congenital CMV infection (cCMV) related to antiviral treatment of pregnant women and infants, the implementation of newborn CMV screening programs, and the frequency and diagnosis of complications among infected children.
Alejandra Sandoval Carmona, Fatima Kakkar, Soren Gantt   +2 more
openaire   +2 more sources

Targeted preemptive therapy according to perceived risk of CMV infection after kidney transplantation

Brazilian Journal of Infectious Diseases, 2016
Background: The identification of the best strategy to manage cytomegalovirus infection is hampered by uncertainties regarding the risk/benefit ratios of universal prophylaxis versus preemptive therapy, the impact of indirect cytomegalovirus effects and ...
Cahue Henrique Pinto, Helio Tedesco-Silva Jr, Claudia Rosso Felipe, Alexandra Nicolau Ferreira, Marina Cristelli, Laila Almeida Viana, Wilson Aguiar, José Medina-Pestana   +7 more
doaj   +1 more source

Incidence of post-transplant cytomegalovirus viremia in patients receiving lungs after ex vivo lung perfusionCentral MessagePerspective

JTCVS Open, 2023
Objectives: Cytomegalovirus infection after lung transplant is associated with increased morbidity and mortality. Inflammation, infection, and longer ischemic times are important risk factors for cytomegalovirus infection.
Rafaela V.P. Ribeiro, MD, PhD, Anas Samman, BSc, Aizhou Wang, PhD, Stella Wang, BSc, MSc, Tereza Martinu, MD, MHS, Shaf Keshavjee, MSc, MD, Lianne G. Singer, MD, Deepali Kumar, MSc, MD, Atul Humar, MSc, MD, Marcelo Cypel, MSc, MD   +9 more
doaj   +1 more source

RNA-binding protein CPEB1 remodels host and viral RNA landscapes. [PDF]

, 2016
Host and virus interactions occurring at the post-transcriptional level are critical for infection but remain poorly understood. Here, we performed comprehensive transcriptome-wide analyses revealing that human cytomegalovirus (HCMV) infection results in
Aigner, Stefan, Ares, Manuel, Batra, Ranjan, Belzile, Jean-Philippe, Bos, Tomas J, Clark, Elizabeth, Donohue, John Paul, Gelboin-Burkhart, Chelsea, Huang, Hui, Huelga, Stephanie C, Rigo, Frank, Roberts, Brett T, Sathe, Shashank, Spector, Deborah H, Stark, Thomas J, Wheeler, Emily C, Yee, Brian A, Yeo, Gene W   +17 more
core   +2 more sources

Human cytomegalovirus-specific CD4+ and CD8+ T-cell reconstitution in adult allogeneic hematopoietic stem cell transplant recipients and immune control of viral infection

Haematologica, 2008
Background Human cytomegalovirus infection is the most frequent viral complication in patients undergoing hematopoietic stem cell transplantation.
Daniele Lilleri, Chiara Fornara, Antonella Chiesa, Daniela Caldera, Emilio Paolo Alessandrino, Giuseppe Gerna   +5 more
doaj   +1 more source

Site-restricted persistent cytomegalovirus infection after selective long-term depletion of CD4+ T lymphocytes [PDF]

, 1989
We have established a murine model system for exploring the ability of a CD4 subset-deficient host to cope with cytomegalovirus infection, and reported three findings.
Jonjic, Stipan, Koszinowski, Ulrich H., Mutter, Wolfgang, Reddehase, Matthias J., Weiland, Frank   +4 more
core   +3 more sources

CMV in the gut: a critical review of CMV detection in the immunocompetent host with colitis. [PDF]

, 2015
As scientific techniques for the detection of cytomegalovirus (CMV) improve, we are able to detect small amounts of CMV in the mucosal wall. As clinicians, we are unsure how to interpret the results of this novel test.
Goodman, AL, Griffiths, PD, Murray, CD, Watkins, J, Webster, DP   +4 more
core   +1 more source

Neutralizing Monoclonal Antibodies Reduce Human Cytomegalovirus Infection and Spread in Developing Placentas. [PDF]

, 2019
Congenital human cytomegalovirus (HCMV) infection is a leading cause of birth defects worldwide, yet the most effective strategies for preventing virus transmission during pregnancy are unknown.
An, Zhiqiang, Fang-Hoover, June, Freed, Daniel C, Fu, Tong-Ming, Li, Fengsheng, Pereira, Lenore, Petitt, Matthew, Tabata, Takako, Wang, Dai   +8 more
core   +1 more source

Genotype distribution, viral load and clinical characteristics of infants with postnatal or congenital cytomegalovirus infection.

PLoS ONE, 2014
BackgroundCongenital cytomegalovirus infection is a leading cause of long-term sequelae. Cytomegalovirus is also frequently transmitted to preterm infants postnatally, but these infections are mostly asymptomatic.
Joppe Nijman, Femke S Mandemaker, Malgorzata A Verboon-Maciolek, Susan C Aitken, Anton M van Loon, Linda S de Vries, Rob Schuurman   +6 more
doaj   +1 more source