Results 191 to 200 of about 2,082,628 (285)

Temperature-dependent benefits and costs of cytoplasmic male sterility in snail <i>Physa acuta</i>. [PDF]

Proc Biol Sci
Bererd S, David P, Teulier L, Plénet S, Luquet E.   +4 more
europepmc   +1 more source

Complete mitochondrial genome sequencing and identification of candidate genes responsible for C5-type cytoplasmic male sterility in cabbage (B. oleracea var. capitata). [PDF]

Front Plant Sci, 2022
Zhong X, Yue X, Cui J, Han R, Gao Y, Kang J.   +5 more
europepmc   +1 more source

Deubiquitination of Vangl by USP6 and USP32 Regulates Planar Cell Polarity Signaling

Advanced Science, EarlyView.
Compartment‐specific deubiquitination controls Vangl dosage and planar cell polarity signaling. USP6 and USP32 regulate distinct subcellular pools of Vangl by removing distinct ubiquitin modifications from Vangl proteins. This regulatory mechanism safeguards PCP‐dependent embryonic morphogenesis, while aberrant USP32‐dependent stabilization of VANGL ...
Fangzi Zha, Di Feng, Ziru Xue, Zhiying Liu, Xiaochen Lin, Zhe Wang, Ling Xu, Jasper Fuk Woo Chan, Martin Cheung, Michael Shing Yan Huen, Yusong Guo, Kui Ming Chan, Yun Liu, Bo Gao   +13 more
wiley   +1 more source

Mitochondrial genome structural variants and candidate cytoplasmic male sterility-related gene in sugarcane. [PDF]

BMC Genomics
Li Y, Li S, Hua X, Xu Y, Chen S, Yu Z, Zhuang G, Lan Y, Yao W, Chen B, Zhang M, Zhang J.   +11 more
europepmc   +1 more source

The TUBA1B–G3BP2 Axis Sustains p65 Transcriptional Activity to Promote Hepatocellular Carcinoma Progression

Advanced Science, EarlyView.
TUBA1B is consistently upregulated in hepatocellular carcinoma and sustains malignant progression by stabilizing G3BP2. By restraining TRIM25‐associated K48‐linked ubiquitination, TUBA1B preserves the G3BP2–IκBα complex and basal NF‐κB/p65 activity. Concurrent TUBA1B/G3BP2 upregulation identifies an aggressive HCC subgroup with enhanced p65 activation ...
Fen Lin, Hechun Lin, Junming Yu, Chao Ge, Lin Mao, Saihua Zhang, Yizi Jin, Yunyu Wu, Taoyang Chen, Jinjun Li, Hong Li   +10 more
wiley   +1 more source

Mitochondrial phylogeny and distribution of cytoplasmic male sterility-associated genes in Beta vulgaris. [PDF]

PLoS One
Kubota K, Oishi M, Taniguchi E, Akazawa A, Matsui K, Kitazaki K, Toyoda A, Toh H, Matsuhira H, Kuroda Y, Kubo T.   +10 more
europepmc   +1 more source

Discovery and Optimization of AMT‐676, a CDH17‐Targeting ADC for the Treatment of Advanced Gastrointestinal Cancers

Advanced Science, EarlyView.
AMT‐676 is a novel antibody‐drug conjugate targeting CDH17, an adhesion molecule uniquely exposed on gastrointestinal tumor surfaces. Engineered with an optimized exatecan payload, it demonstrates profound tumor regression and a robust bystander effect across diverse preclinical models.
Ying‐nan Wang, Dan‐yun Ruan, Jing Shi, Yue Huang, Hui Sheng, Ya‐ling Huang, Linjie Ma, Lijun Wang, Caiwei Chen, Yixuan Wang, Yue Zhang, Yi Shen, Qing Zhang, Jianjian Zhang, Yanfang Tang, Jin‐ling Zhang, Jia‐jia Hu, Chen‐yi Wu, Jia‐ying Chen, Xun Meng, Shu‐Hui Liu, Feng Wang   +21 more
wiley   +1 more source

Identification, Elucidation and Deployment of a Cytoplasmic Male Sterility System for Hybrid Potato. [PDF]

Biology (Basel)
Eggers EJ, Su Y, van der Poel E, Flipsen M, de Vries ME, Bachem CWB, Visser RGF, Lindhout P.   +7 more
europepmc   +1 more source

DLST Succinylation‐Mediated Mitochondrial Metabolic Remodeling and Cuproptosis Resistance Promote Malignant Progression of Lung Adenocarcinoma

Advanced Science, EarlyView.
The DLST K409 succinylation mediated by CPT1A promotes OXPHOS and redox homeostasis through regulating enzyme activity, thereby promoting the malignant progression of LUAD. Notably, the succinylation of DLST can enhance the cuproptosis resistance by inhibiting its lipoylation.
Xuanxuan Li, Peijun Zhou, Xingzhi Peng, Qixin Liu, Wenhui Zeng, Rui Wang, Liangfang Shen, Jinwu Peng, Qin Zhou, Lifang Yang   +9 more
wiley   +1 more source

The Effects of DNA Methylation on Cytoplasmic Male Sterility in Sugar Beet. [PDF]

Int J Mol Sci
Weng J, Wang H, Cheng D, Liu T, Zeng D, Dai C, Luo C.   +6 more
europepmc   +1 more source