Results 161 to 170 of about 279,754 (316)

Targeting ROCK2 to Restore Epileptic Synaptic Networks via Mitophagy Activation: Insights from Translational Imaging of SV2A In Vivo

open access: yesAdvanced Science, EarlyView.
By integrating synaptic vesicle glycoprotein 2A PET imaging and transcriptomics, this study identifies Rho‐associated protein kinase 2 (ROCK2) as a critical regulator of synaptic network dysfunction in temporal lobe epilepsy. Pharmacological ROCK2 inhibition restores synaptic density and enhances mitophagy, thereby reducing seizures and neuronal damage.
Ling Xiao   +14 more
wiley   +1 more source

Multi-year study monitoring the mercury content in the tissues of cattle sampled in the Czech Republic between 2014 and 2023. [PDF]

open access: yesVet Med (Praha)
Svoboda M   +8 more
europepmc   +1 more source

A Degradable Bioinspired Flier with Aerogel‐Based Colorimetric Sensors for Environmental Monitoring

open access: yesAdvanced Science, EarlyView.
Biodegradable fliers are developed inspired by Tipuana tipu samaras, integrating cellulose nanocrystal aerogel (CNCa) sensors loaded with natural dyes for pH and ammonia detection. The lightweight, degradable fliers mimic natural morphology and aerodynamics, offering an eco‐friendly, scalable solution for in situ environmental monitoring after passive ...
Gianpaolo Gallo   +4 more
wiley   +1 more source

Cryptosporidium geckonae n. sp. (Apicomplexa: Cryptosporidiidae) in geckos. [PDF]

open access: yesParasit Vectors
Zikmundová V   +9 more
europepmc   +1 more source

Serine Grafted Silica Coated Nanoscale Zero‐Valent Iron with Enhanced Fenton‐Like Degradation of Mixed Organic Solvents of Tributyl Phosphate and n‐dodecane

open access: yesAdvanced Science, EarlyView.
Serine grafted silica coated nanoscale zero‐valent iron is synthesized. Through the SiO2 coating and serine grafting, the aggregation and oxidation of nZVI are reduced, and the slow release of Fe2+ ensured the catalytic cycle. The adsorption capacity for TBP and n‐dodecane is higher, because of the synergistic effect of surface functional groups.
Peijie Sun, Haifeng Xu, Lejin Xu
wiley   +1 more source

Deep Learning‐Powered Nanoplasmonic Biosensing Approach Enables Ultrasensitive Extracellular Vesicles Profiling for Cancer Screening

open access: yesAdvanced Science, EarlyView.
This study presents a Kolmogorov–Arnold network (KAN)‐powered nanoplasmonic biosensing platform for ultrasensitive detection of small extracellular vesicles in serum, enabling highly accurate pancreatic cancer screening. The method achieves an area under the curve (AUC) of 0.99 in a large clinical cohort, offering a robust and interpretable deep ...
Jiaheng Zhu   +21 more
wiley   +1 more source

Artificial intelligence-assisted chest radiograph interpretation in Role 2 military field hospital settings: a controlled experimental study. [PDF]

open access: yesTrauma Surg Acute Care Open
Májovský M   +22 more
europepmc   +1 more source

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