Results 211 to 220 of about 279,754 (316)

Development of an efficient mice model of cancer‐associated cardiac cachexia

Animal Models and Experimental Medicine, EarlyView.
This work establishes a preclinical framework for targeting ubiquitin pathways to mitigate the morbidity of cancer‐related cardiopathy. Our integrated approach delineates a hierarchical progression from subcellular dysfunction to macroscopic cardiac deterioration. These findings mechanistically link tumor‐induced cachexia to cardiac dysfunction through
Shijie Xiong, Huiting Zheng, Teng Wu, Jing Tan, Tongsheng Huang, Conghui Shen, Yuanjun Ji, Mengying Liu, Junhong Wan, Weibin Cai   +9 more
wiley   +1 more source

Surface‐Decoupled Altitudinal and Azimuthal Triptycene‐Fused Tetrapodal Molecular Motors

Angewandte Chemie, EarlyView.
Two tetrapodal triptycene‐based light‐driven molecular motors with precisely oriented rotation axes—parallel or perpendicular to a gold surface—achieve full 360° rotation in both solution and as monolayers. The design minimizes surface quenching, enabling functional integration into surface‐mounted nanomachines.
Kateřina Bezděková, Lukáš Severa, Eva Kaletová, Katarina Majerová Varga, Milan Mašát, Liang‐Ting Wu, Jyh‐Chiang Jiang, Ivana Císařová, Jiří Kaleta   +8 more
wiley   +2 more sources

Genetic drivers of liver cirrhosis: The role of SERPINA1 and PNPLA3 variants in disease onset and progression. [PDF]

PLoS One
Holinka M, Frankova S, Adamcova Selcanova S, Skladany L, Fabian O, Kveton M, Merta D, Adamkova V, Hubacek JA, Pitova V, Vesela S, Hucl T, Jirsa M, Sperl J.   +13 more
europepmc   +1 more source

Targeted Proteomics upon Treatment with Tofersen Identifies Novel Response Markers for Superoxide Dismutase 1‐Linked Amyotrophic Lateral Sclerosis

Annals of Neurology, EarlyView.
Objective Tofersen is the first effective and approved therapy for superoxide dismutase 1 (SOD1)‐associated amyotrophic lateral sclerosis (ALS [SOD1‐ALS]). Following treatment with tofersen, neurofilament levels in patients' cerebrospinal fluid (CSF) and serum seem to respond earlier than clinical parameters.
Christina Steffke, Karthik Baskar, Franziska Bachhuber, Maximilian Wiesenfarth, Johannes Dorst, Joachim Schuster, Florian Schöberl, Peter Reilich, Martin Regensburger, Alexander German, René Günther, Maximilian Vidovic, Susanne Petri, Thomas Meyer, Tim Hagenacker, Julian Grosskreutz, Ute Weyen, Patrick Weydt, Thomas Haarmeier, Paul Lingor, Joachim Wolf, Andreas Hermann, Johannes Prudlo, Kornelia Günther, Antje Knehr, Zeynep Elmas, Zeljko Uzelac, Simon Witzel, Wolfgang Philipp Ruf, Axel Freischmidt, Ritchie Ho, Albert C. Ludolph, Jochen H. Weishaupt, Hayrettin Tumani, Patrick Oeckl, David Brenner, Alberto Catanese   +36 more
wiley   +1 more source

Engagement, self-efficacy and self-regulation as predictors of academic success in non-medical healthcare education. [PDF]

BMC Med Educ
Martincová J, Staňková I, Snopek P, Zemánková L.   +3 more
europepmc   +1 more source

Intragenic <i>TTN</i> Deletions in a Single Family with Dilated Cardiomyopathy. [PDF]

Appl Clin Genet
Wayhelova M, Peldova P, Krebsova A, Nemcikova M, Sojka M, Macek M.   +5 more
europepmc   +1 more source

Effect of second-hand smoking on the incidence of postoperative nausea and vomiting in children after adenoidectomy: a single-centre retrospective study. [PDF]

J Anesth Analg Crit Care
Frelich M, Burša F, Jor O, Vodička V, Křenková K, Vítková N, Kondé A, Parma M, Buršík D, Šámaj P, Walachová N, Kantor P, Hranková V, Motalová S, Sklienka P.   +14 more
europepmc   +1 more source

The Czech National Identity

, 1997
Alena Nedomová, Tomáš Kostelecký
openalex   +1 more source

Author Correction: Cytokinin depends on GA biosynthesis and signaling to regulate different aspects of vegetative phase change in Arabidopsis. [PDF]

Nat Commun
Werner S, Tarkowskà D, Schmülling T.
europepmc   +1 more source

Efficacy and safety of intravenous sufentanil administration in low-severity acute trauma as a competence of paramedics: a follow-up observational study. [PDF]

Eur J Trauma Emerg Surg
Sykora R, Kukackova N, Sopko O, Peran D, Smetana J, Renza M, Kukacka M.   +6 more
europepmc   +1 more source