British Journal of Pharmacology, EarlyView.Addressing complexity in the study of life sciences through Systems Biology and Systems Medicine has been transformative, making Systems Pharmacology the next logical step. In this review, we focus on physical stimuli, whose potential in pharmacology has been neglected, despite demonstrated therapeutic properties.
Veronica Paparozzi +10 more
wiley +1 more source
Mortality patterns in multimorbid populations: cross-sectional population-wide analysis of Czech national registry data, 2014-2023. [PDF]
BMJ OpenUkolova B, Strozza C.
europepmc +1 more source
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Immune tolerance prevents inflammation and autoimmunity, with dendritic cells (DCs) playing a key role. Reprogramming DCs towards a tolerogenic state represents a promising therapeutic strategy. Sulforaphane (SFN) has known immunomodulatory effects, but its clinical application is limited by poor stability and ...
María Elena Angarita‐Planchez +6 more
wiley +1 more source
First report of Usutu virus fatal infections in Chilean tinamous (Nothoprocta perdicaria), brahminy starlings (Sturnia pagodarum), and multiple other bird species in zoological gardens and wildlife in the Czech Republic. [PDF]
One Health OutlookKamiš J +12 more
europepmc +1 more source
Importance of snowmelt contribution to seasonal runoff and summer low flows in Czechia [PDF]
, 2020 Michal Jeníček, Ondřej Ledvinka
openalex +1 more source
Child &Family Social Work, EarlyView.ABSTRACT Understanding social factors that affected how people interpreted the meanings of COVID‐19 measures is important in postpandemic times. This study applies perspectives from research on emotions as one of the possible explanations and focuses on how institutions and their measures are perceived in the context of individual emotional situations.
Eva M. Hejzlarová
wiley +1 more source
Noonan syndrome spectrum disorders in real life: patient characteristics and response to growth hormone therapy in a genetically defined single-country multicenter cohort. [PDF]
Eur J PediatrJirova B +20 more
europepmc +1 more source
“Golden Prague”, “a Promised South” and the rest...? Regional and settlement preferences of the inhabitants of Czechia [PDF]
, 2014 Marie Štefánková, Dušan Drbohlav
openalex +1 more source
UBVH: Unified Bounding Volume and Scene Geometry Representation for Ray Tracing
Computer Graphics Forum, EarlyView.Abstract Bounding volume hierarchies (BVHs) are currently the most common data structure used to accelerate ray tracing. The existing BVH methods distinguish between the bounding volume representation associated with the interior BVH nodes and the scene geometry representation associated with leaf nodes.
M. Káčerik, J. Bittner
wiley +1 more source
Epidemiology of human salmonellosis in Czechia ─ a country with the highest European notification rate, 2012 to 2023. [PDF]
Euro SurveillŠpačková M +5 more
europepmc +1 more source