Results 211 to 220 of about 15,264 (259)

Behavioral Assessment of Tramadol and Meloxicam Effects on Postoperative Pain in a Rat Craniotomy Model. [PDF]

J Am Assoc Lab Anim Sci
Alemán-Laporte J, Alvarado G, Pellagio NB, Fonseco Brasil Antiorio AT, Zanatto DA, Fornaguera J, Carvajal MRM, Mori CMC.   +7 more
europepmc   +1 more source

Infusible Extracellular Matrix Biomaterial Enhances Cell‐Specific Pro‐Repair Responses Following Acute Myocardial Infarction

Advanced Healthcare Materials, EarlyView.
We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin, Alexander Chen, Quincy P. Lyons, Michael B. Nguyen, Maria L. Karkanitsa, Justin Yu, Van K. Ninh, Emily Gardner, Elyse G. Wong, Sriya N. Paleti, Julian Cheng, Benjamin D. Bridgelal, Kate E. Reimold, Selena Cao, Connor Uhre, Colin G. Luo, Zhenxing Fu, Kevin R. King, Karen L. Christman   +18 more
wiley   +1 more source

Detection of Fusion Genes Using RNA Sequencing in Acute Leukemia. [PDF]

Ann Lab Med
Kim HY, Kim B, Park MS, Park JH, Ju HY, Yoo KH, Jang JH, Jung CW, Kim HJ.   +8 more
europepmc   +1 more source

Genipin‐Crosslinked, Silane‐Anchored 3D Tumor–Stroma Microtissues for High‐Content On‐Chip Drug Testing

Advanced Healthcare Materials, EarlyView.
We describe a microfluidic tumor‐stroma co‐culture model, engineered to resist collagen‐hydrogel contraction driven by fibroblast activity. Surface silanization with APTES covalently anchors the matrix to the chip, while Genipin crosslinking progressively increases stiffness and elasticity without harming cells. This supports >10 days of co‐culture and
Doriane Le Manach, Reza Kowsari‐Esfahan, Emilia Reszczyńska, Philippe Nghe, Matthias Nees   +4 more
wiley   +1 more source

The editable landscape of the yeast genome reveals hotspots of structural variant formation. [PDF]

Sci Adv
Li S, Vonesch SC, Roy KR, Tu CS, Steudle F, Nguyen M, Jann C, Steinmetz LM.   +7 more
europepmc   +1 more source

Laser‐Assisted Processing and Modification of Bioactive Glasses: A Review

Advanced Healthcare Materials, EarlyView.
Laser technologies provide powerful tools to process and transform bioactive glasses for advanced biomedical applications. This review discusses laser‐matter interaction mechanisms, laser surface engineering, and laser‐assisted fabrication of scaffolds and nanofibers.
Antonio Riveiro, Mario González‐Quintas, Mónica Fernández‐Arias, Jesús del Val, Félix Quintero, Rafael Comesaña, Fernando Lusquiños, Julian R. Jones, Juan Pou   +8 more
wiley   +1 more source

Novel CRISPR-Cas9 iPSC knockouts for PCCA and PCCB genes: advancing propionic acidemia research. [PDF]

Hum Cell
García-Tenorio EM, Álvarez M, Gallego-Bonhomme M, Desviat LR, Richard E.   +4 more
europepmc   +1 more source

Paracrine Factor Local Gradient‐Generating System for Engineering Perfusable Vascularized Hepatocyte Tissues with Perfusion‐Induced Proliferation

Advanced Healthcare Materials, EarlyView.
A paracrine factor local gradient (PFLG)‐generating system enables microvessel penetration across 3D hepatocyte tissues. The resulting vascularized constructs recapitulate hepatic sinusoidal hepatocyte—endothelial contact architecture and enhance hepatic functions in vitro.
Yen‐Hsiang Huang, Tadahiro Yamashita, Ryo Sudo   +2 more
wiley   +1 more source

Immunologic effects of locoregional therapies for unresectable hepatocellular carcinoma. [PDF]

JHEP Rep
Schmidt R, Gebauer B, Akbari N, Roderburg C, Torsello GF, Fehrenbach U, Auer TA, Mohr R, Ardila Pardo GL, Lim W, Pivetta F, Can E, Hamm CA, Tacke F, Hamm B, Hammerich L, Savic LJ.   +16 more
europepmc   +1 more source

Optoelectrical Devices for Neural Interfacing: Engineering Integration, Stability, and Multimodal Sensing

Advanced Healthcare Materials, EarlyView.
Implantable optoelectrical devices are an effective resource for the modulation and monitoring of neural activity with high spatiotemporal resolution. This review discusses current challenges faced by these devices and outlines future perspectives for the development of next‐generation neural interfaces targeting chronic, multisite, and multimodal ...
Stella Aslanoglou, Barbara Spagnolo, Antonio Balena, Massimo De Vittorio, Ferruccio Pisanello   +4 more
wiley   +1 more source