Results 41 to 50 of about 129,060 (263)

Deudas soberanas europeas y esfuerzos en pos de la estabilidad [PDF]

open access: yes, 2010
Tratando de superar la crisis financiera global, los gobiernos se endeudaron, en gran medida, y aumentaron sus déficit fiscales, sentando así las bases de una crisis de deudas soberanas.
Chapoy Bonifaz, Alma
core  

Decoupling Dynamics and Crosslink Stability in Supramolecular Hydrogels Using Associative Exchange

open access: yesAdvanced Materials, EarlyView.
How does reorganization impact the stability of supramolecular hydrogels? In contrast to dissociative crosslink exchange, implementing associative exchange in macroscale DNA hydrogels enables decoupling of reorganization dynamics from thermal and mechanical stability.
Pierre Le Bourdonnec   +4 more
wiley   +1 more source

Sobre la conveniencia de la regla fiscal

open access: yesRevista de la Facultad de Derecho, 2021
La discusión acerca de la adopción de una regla fiscal (entendida como una restricción permanente al crecimiento del gasto público) en un tratados internacionales, la Constitución o la legislación ordinaria, debe partir del análisis de los efectos ...
Andrés Blanco
doaj   +1 more source

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

open access: yesAdvanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao   +16 more
wiley   +1 more source

Fiscal regime changes and the sustainability of fiscal imbalance in South Africa: a smooth transition error-correction approach

open access: yesSouth African Journal of Economic and Management Sciences, 2012
In addition to the conventional linear cointegration test, this paper tests the asymmetry relationship between fiscal revenue and expenditure, by making a distinction between the adjustment of positive (budget surplus) and negative (budget deficit ...
Samuel Jibao   +2 more
doaj   +1 more source

Gut Microbiota‐Derived Anandamide Mediates the Therapeutic Effects of Urolithin A on Alcohol‐Induced Cognitive and Social Dysfunction via CB1R‐DRD2‐RAP1 Signaling Axis

open access: yesAdvanced Science, EarlyView.
This study reveals that Urolithin A (UA) counteracts alcohol‐induced cognitive and social dysfunction (AICSD) via a gut microbiome‐dependent mechanism. UA‐enriched Bacteroids sartorii and Parabacteroids distasonis elevate anandamide (AEA), which activates the CB1R‐DRD2‐Rap1 signaling cascade to drive synaptic repair and reduce neuroinflammation ...
Hongbo Zhang   +9 more
wiley   +1 more source

Testing the Validity of the Triple Deficit Hypothesis for Nigeria

open access: yesEconometric Research in Finance, 2019
This paper tests the validity of the triple deficit hypothesis in Nigeria by examining the causal relationship among current account deficit, financial account deficit, and fiscal deficit within a five-variate ARDL framework complemented with GMM ...
Rahman Olanrewaju Raji
doaj   +1 more source

Modelo de recuperación de la inversión pensional en el régimen RAIS [PDF]

open access: yes, 2017
Trabajo de investigaciónSe desarrolla un modelo de simulación para evaluar la mejor opción de acuerdo con las condiciones de cada trabajador, apoyándolo en la decisión de escoger el plan pensional que más le ha de convenir en el ahorro para su vejez.
León-Castañeda, Herly Johana   +2 more
core   +1 more source

Versatile CRISPR‐Cas Tools for Gene Regulation in Zebrafish via an Enhanced Q Binary System

open access: yesAdvanced Science, EarlyView.
This study introduces CRISPR‐Q, a transgenic CRISPR‐Cas system leveraging the QFvpr/QUAS binary expression platform in zebrafish. CRISPR‐Q overcomes previous challenges in achieving stable and efficient gene regulation. By enabling precise spatiotemporal control of transcript knockdown (CRISPR‐QKD) and gene activation (CRISPR‐Qa), it provides a ...
Miaoyuan Shi   +13 more
wiley   +1 more source

The European Fiscal Rules Need Major Reforms

open access: yesWirtschaftsdienst, 2022
The European fiscal rules are to be reactivated in 2023 or 2024. In their current form, they pose a significant threat to economic recovery and the investment urgently required to achieve climate neutrality.
Carl Mühlbach
doaj   +1 more source

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