Results 51 to 60 of about 124,512 (193)

Long‐Term Effects of Xenotransplantation of Human Enteric Glia in an Immunocompetent Rat Model of Acute Brain Injury

Advanced Science, EarlyView.
Acute brain injuries are characterized by extensive tissue damage, resulting in debilitating deficits in patients. Despite considerable progress, cell‐based approaches have yet to identify an ideal candidate. This long‐term study explores the use of an untested cell source – human enteric glia – and a non‐invasive administration route – intranasal ...
Nina Colitti, Edwige Rice, Franck Desmoulin, Maylis Combeau, Mélissa Parny, Lorenne Robert, Etienne Buscail, Barbara Bournet, Nathalie Vergnolle, Isabelle Raymond‐Letron, Isabelle Loubinoux, Carla Cirillo   +11 more
wiley   +1 more source

La sombra de Las Torres Gemelas: los déficits de la "Reaganomic" sobre la bolsa de valores [PDF]

, 1987
Con la caída de la bolsa de valores se ha señalado al déficit comercial junto con el déficit fiscal como las causas fundamentales del crac bursátil. Además, está generalmente aceptado que no habrá una mejora definitiva en la bolsa hasta que Reagan tome ...
Levine, Elaine
core  

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

An Empirical Analysis on the Relationship between Fiscal Deficit and Inflation in Nigeria [PDF]

Annals of Dunarea de Jos University. Fascicle I : Economics and Applied Informatics, 2014
The implications of fiscal deficits on key macroeconomic variables have led to a large body of literature examining the question of whether economies with large and persistent fiscal deficits have high inflation rate.
Mika’ilu ABUBAKAR, Haruna Mohammed ALIERO, Ali Danjumah UMARU   +2 more
doaj  

Gut Microbiota‐Derived Anandamide Mediates the Therapeutic Effects of Urolithin A on Alcohol‐Induced Cognitive and Social Dysfunction via CB1R‐DRD2‐RAP1 Signaling Axis

Advanced Science, EarlyView.
This study reveals that Urolithin A (UA) counteracts alcohol‐induced cognitive and social dysfunction (AICSD) via a gut microbiome‐dependent mechanism. UA‐enriched Bacteroids sartorii and Parabacteroids distasonis elevate anandamide (AEA), which activates the CB1R‐DRD2‐Rap1 signaling cascade to drive synaptic repair and reduce neuroinflammation ...
Hongbo Zhang, Zibin Li, Yao Xiao, Ji Bian, Caian He, Chao Liu, Lan Gong, Lin Han, Zhigang Liu, Min Wang   +9 more
wiley   +1 more source

MODERATING ROLE OF INFLATION ON THE RELATIONSHIP BETWEEN PUBLIC DEBT AND PRIVATE INVESTMENT IN SOUTH AFRICA

Gusau Journal of Accounting and Finance
South Africa faces a persistent decline in private investment amid rising public debt and inflation volatility, raising concerns about the long-term sustainability of its fiscal and economic trajectory.
Oloruntoba Oyedele
doaj   +1 more source

Nurr1 Orchestrates Claustrum Development and Functionality

Advanced Science, EarlyView.
Nurr1 (Nr4a2) is the master transcription factor to control claustrum morphogenesis and cell fate decision postmitotically by inhibiting intracellular G‐protein signaling. Nurr1 deficiency alters the transcriptomic profiles of subcortical claustral neurons into neocortical insular neurons, resulting in defected claustrum development, impaired axonal ...
Kuo Yan, Andrew G. Newman, Pauline Lange, Susanne Müller, Marco Foddis, Stefan Paul Koch, Philipp Böhm‐Sturm, Maron Mantwill, Carsten Finke, Penghui Deng, Melissa Long, Dietmar Schmitz, Victor Tarabykin   +12 more
wiley   +1 more source

El costo Económico de la Incertidumbre [PDF]

Este ensayo fue escrito originalmente en 1987, como un panfleto a favor del equilibrio fiscal. La situación económica argentina era entonces definitivamente distinta y peor. En esta oportunidad, he agregado un conjunto de estimaciones econométricas sobre
Jorge C. Ávila
core  

Versatile CRISPR‐Cas Tools for Gene Regulation in Zebrafish via an Enhanced Q Binary System

Advanced Science, EarlyView.
This study introduces CRISPR‐Q, a transgenic CRISPR‐Cas system leveraging the QFvpr/QUAS binary expression platform in zebrafish. CRISPR‐Q overcomes previous challenges in achieving stable and efficient gene regulation. By enabling precise spatiotemporal control of transcript knockdown (CRISPR‐QKD) and gene activation (CRISPR‐Qa), it provides a ...
Miaoyuan Shi, Weiqi Ge, Changheng Li, Bin Liu, Xiaoyi Deng, Chengjie Liu, Meijun Zheng, Pu Zhang, Lei Li, Ying Guo, Yunqi Han, Yu Yang, Yanxun V. Yu, Youngnam N. Jin   +13 more
wiley   +1 more source

Verificación empírica de una regla de política económica sobre el déficit fiscal para Colombia

Ensayos de Economía, 2014
Este documento busca derivar una regla de política fiscal y verificarla empíricamente para la economía colombiana. La regla fiscal utiliza el déficit fiscal primario como instrumento en función de la brecha del producto y los desvíos de la tasa inflación.
Juan Camilo Galvis Ciro
doaj