Results 101 to 110 of about 641,558 (244)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Counting eigenvalues in domains of the complex field [PDF]

open access: yes, 2011
A procedure for counting the number of eigenvalues of a matrix in a region surrounded by a closed curve is presented. It is based on the application of the residual theorem.
Kamgnia, Emmanuel R., Philippe, Bernard
core   +4 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Determinant Earning Management

open access: yesIJEBD (International Journal of Entrepreneurship and Business Development)
Purpose: This study tries to identify "the influence of sales growth, tax planning, firm size and profitability on earnings management (case study of consumer goods sector companies listed on IDX in 2017-2021)" Design/methodology/approach: This ...
Saiful Anam   +3 more
doaj   +1 more source

La grammaticalisation de l'enfance en haoussa [PDF]

open access: yes, 2008
The synchronic study of one lexical term through the various grades of the linguistic scale (lexicon, nominal or verbal phrase, interpropositional) allows for the analysis of the diachronic process of grammaticalization and of language in general.
Caron, Bernard
core   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Taux et déterminant de l’adoption des innovations agricoles au Sénégal : le cas des semences certifiées

open access: yesScience, Technologie, Développement
L’objectif de cet article est d’estimer les taux et les facteurs d’adoption déterminant les semences certifiées développées par les institutions de recherche. En utilisant des données d’enquêtes agricoles annuelles (EAA) de la Direction de l’Analyse,
Babacar NDIAYE, Adja Mariata Rella TALL
doaj   +1 more source

Enchaînement, liaison, accentuation chez les apprenants norvégophones [PDF]

open access: yes, 2015
Given that their L1, Norwegian, and their L2, English, are lexical stress languages, Norwegian speakers will equally tend to stress lexical words during the course of acquisition of L3 French, insuring the prosodic autonomy of each word.
Andreassen, Helene N., Lyche, Chantal
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

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