Results 141 to 150 of about 1,082,991 (241)

Codon Optimality Is a Major Determinant of mRNA Stability

open access: yesCell, 2015
Vladimir Presnyak   +10 more
semanticscholar   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

L’orientation à l’entrée à l’université comme facteur déterminant l’expérience sociale des étudiants de première année

open access: yesRevue des Sciences Humaines, 2010
Cette recherche s’inscrit dans une approche sociologique de l’orientation. Elle vise plus particulièrement l’étude de « l’entrée à l’université » comme facteur déterminant l’expérience sociale de l’étudiant de première année.
Chafika BOULKOUR
doaj  

Le module de reformulation iconique de la Plateforme de Communication Alternative

open access: yes, 2007
International audienceWe present the reformulation system embedded in "Plateforme de Communication Aternative", an assistive communication software destinated to impaired persons.
Blache, Philippe, Rauzy, Stéphane
core   +1 more source

Gender/Sex as a Social Determinant of Cardiovascular Risk.

open access: yesCirculation, 2018
A. O'Neil   +3 more
semanticscholar   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Determinants of tridiagonal matrices over some commutative finite chain rings

open access: yesSpecial Matrices
Diagonal matrices and their generalization in terms of tridiagonal matrices have been of interest due to their nice algebraic properties and wide applications.
Jitman Somphong, Sricharoen Yosita
doaj   +1 more source

Respiration as the main determinant of carbon balance in European forests

open access: yesNature, 2000
R. Valentini   +29 more
semanticscholar   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

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