Results 181 to 190 of about 538,912 (199)

Response to the Letter to the Editor Entitled "Beyond Lymphocytic Inflammation: Immune Architecture as a Determinant of Renal Outcomes". [PDF]

Kidney Int Rep
Boudhabhay I, Isnard P.
europepmc   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Aerosol Delivery With a Vibrating Mesh Nebulizer Across Tidal Volume-Based Pediatric Invasive Ventilation Models: An In Vitro Evaluation. [PDF]

Crit Care Explor
Miura S, Igarashi Y, Shono K, Shima S, Kawaguchi A.   +4 more
europepmc   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

A Multi-Framework Approach to Medication Adherence Evaluation in Pharmacy Student-Led Medication Reviews: An Observational Exploratory Study. [PDF]

Pharmacy (Basel)
Keidong H, Valge M, Laisaar KT, Cavaco AMDN, Volmer D.   +4 more
europepmc   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Determinants of Health Literacy-Tailored Communication Practices Adoption in French Community Pharmacies: A Theoretical Domains Framework Mixed-Methods Study. [PDF]

Health Sci Rep
Rambure M, Perrin A, Rossello N, Chenet E, Marchal M, Dima AL, Bravant E, Viprey M, Schott AM, Haesebaert J.   +9 more
europepmc   +1 more source

Microbes and minutes: The hidden but key role of time in infection control and stewardship. [PDF]

New Microbes New Infect
Al-Tawfiq JA, Schlagenhauf P.
europepmc   +1 more source