Results 221 to 230 of about 887,625 (261)

Climate change and malaria control in Africa: country experiences and strategic responses. [PDF]

Malar J
Yahouedo AG, Merle CS, Diallo I, Ndiop M, Muhire A, Mukashema C, Mutabazi A, Hakizimana E, Muteba C, Kaseba AN, Tanoh MA, Aimain AS, Coulibaly KA, Razanakotomalala V, Diar MSI, Djaskano MI, Kodindo I, Ayala D, Caminade C, Diouf I, de Chevigny T, Ngou O, Pothin E, Girond F, Tchouatieu AM, Fleutelot E, Noseda V, Deuve JL.   +27 more
europepmc   +1 more source

14‐3‐3σ up‐regulation in the temporal cortex associates with tau pathology and reactive astroglia in Lewy body disorders

Brain Pathology, EarlyView.
14‐3‐3 protein homeostasis is disrupted in Lewy body pathology, showing a diminution of six isotypes and overexpression of stratifin. The latter was associated with stratifin colocalization with tau pathology and reactive astrocytes. Platelets, as a peripheral biomarker source, mirrored inversely cortical 14‐3‐3 gene expression patterns in dementia ...
Laura Marsal‐García, Jorge Mena, Carol‐Ann Lao, David Adamuz, Laura Arnaldo, Cristina Carrato, Alex Menendez, Daniela Samaniego, Dolores Vilas, Lourdes Ispierto, Anna Planas, Ramiro Alvarez, Pau Pastor, Katrin Beyer   +13 more
wiley   +1 more source

Reply to Wüster et al. On the Importance of Correct Snake Identification. Comment on "Chippaux et al. Snakebites in Cameroon by Species Whose Effects Are Poorly Described. Trop. Med. Infect. Dis. 2024, 9, 300". [PDF]

Trop Med Infect Dis
Chippaux JP, Taieb F.
europepmc   +1 more source

Rapid generation of prion disease models using AAV‐delivered PrP variants in knockout mice

Brain Pathology, EarlyView.
We developed a rapid AAV‐based system to generate prion disease models in weeks rather than months. Following systemic AAV9P31 delivery of modified PrP to knockout mice, we achieved brain‐wide expression and successful propagation of both classical (RML) and atypical (GSS‐A117V) prion strains.
Maitena San‐Juan‐Ansoleaga, Eva Fernández‐Muñoz, Jorge M. Charco, Enric Vidal, Diego Herrero‐Martínez, Josu Galarza‐Ahumada, Cristina Sampedro‐Torres‐Quevedo, Samanta Giler, Mariví Geijo, Gloria González‐Aseguinolaza, Hasier Eraña, Joaquín Castilla   +11 more
wiley   +1 more source

Series 1: Behind the Spread: A Scoping Review of Risk Factors for Exposure to <i>Mycobacterium tuberculosis</i>. [PDF]

Trop Med Infect Dis
Menon S, Harries AD, Dlodlo RA, Badoum G, Dogo MF, Mbitikon OB, Sinha P, Lin Y, Jaju J, Soe AN, Singh A, Kalottee B, Koura KG.   +12 more
europepmc   +1 more source

The L108I polymorphism in mouse prion protein drives spontaneous disease and enhances transmission of atypical and classical prion strains

Brain Pathology, EarlyView.
A single amino acid change (L108I) combined with PrP overexpression drives spontaneous atypical prion formation in mice, enabling also efficient propagation of diverse prion strains. This model allows studying how spontaneous prion diseases arise and provides powerful tools for investigating strain emergence, transmission barriers, and mechanisms ...
Hasier Eraña, Enric Vidal, Natalia Fernández‐Borges, Jorge M. Charco, Carlos M. Díaz‐Domínguez, Cristina Sampedro‐Torres‐Quevedo, Josu Galarza‐Ahumada, Eva Fernández‐Muñoz, Maitena San‐Juan‐Ansoleaga, Miguel Ángel Pérez‐Castro, Nuno Gonçalves‐Anjo, Patricia Piñeiro, Samanta Giler, Nora González‐Martín, Nuria L. Lorenzo, Africa Manero‐Azua, Guiomar Perez de Nanclares, Mariví Geijo, Manuel A. Sánchez‐Martín, Jesús R. Requena, Joaquín Castilla   +20 more
wiley   +1 more source

The territory, at the heart of new fish-farming innovations [PDF]

, 2017
Da Silva, Newton José Rodrigues, Dabbadie, Lionel, Henry, François, Mikolasek, Olivier, Oswald, Marc   +4 more
core  

Divergence in μ and δ opioid receptor pharmacology in neurons and antinociceptive efficacy in neuropathic pain: Insights from MP135 and CYM51010

British Journal of Pharmacology, EarlyView.
Background and purpose Opioids targeting the μ opioid receptor remain largely ineffective in neuropathic pain conditions, emphasizing the need for novel therapeutic strategies. MP135 was reported to reduce thermal nociception in naive animals by activating μ‐δ opioid receptor heteromers.
Perrine Inquimbert, Chantal Fitterer, Sylvain Hugel, Mila Jesic, Yannick Goumon, Virgine Andry, Severine Schneider, Francois Daubeuf, Abdelfattah Faouzi, Stephane Doridot, Susruta Majumdar, Frederic Bihel, Martine Schmitt, Dominique Massotte   +13 more
wiley   +1 more source

A Multi-Host Approach to Quantitatively Assess the Role of Dogs as Sentinels for Rift Valley Fever Virus (RVFV) Surveillance in Madagascar. [PDF]

Viruses
Ramaroson HS, Garchitorena A, Lacoste V, Andriamandimby SF, Schoenhals M, Bastard J, Albrechtova K, Chevalier LJG, Rakotomanana D, Rasamoel PV, Raliniaina M, Andriamahefa HF, Andriamananjara MA, Rasoloharimanana LT, Razafimahatratra SL, Ratsimbasoa CA, Durand B, Chevalier V.   +17 more
europepmc   +1 more source