Results 231 to 240 of about 887,625 (261)

Latin America regional strategy document. 2002-2006 programming. April 2002 [PDF]

, 2002

core  

Enhancing antitumour response to proteasome inhibitors with inhibitors of insulin‐degrading enzyme, a new molecular vulnerability in multiple myeloma

British Journal of Pharmacology, EarlyView.
Inhibitors of insulin‐degrading enzyme boost PI cytotoxicity through an increased sensitivity of proteasome to PI inhibitors, induction of ISR, DNA damage and Myc down‐regulation. They overcome PI resistance in vitro and induce tumour regression in vivo.
Laetitia Lesire, Rebecca Deprez‐Poulain, Damien Bosc, Florence Leroux, Valerie Landry, Sarah Ourabah, Morgane Tardy, Clara Maillard, Ronan Gealageas, Julie Dumont, Adrien Herledan, Sandrine Warenghem, Manon Cruette, Celine Lenglart, Alexandre Biela, Catherine Piveteau, Eva De Smedt, Catharina Muylaert, Wenguang Liang, Elvira Garcia De Paco, Elina Alaterre, Sara Ovejero, Nicolas Robert, Fabien Delahaye, Wei‐Jen Tang, Peter van Endert, Elke De Bruyne, Jérôme Moreaux, Benoit Deprez   +28 more
wiley   +1 more source

30,000 years of fire history in the Cerrado. [PDF]

Sci Rep
Ledru MP, Franco Cassino R, Escobar-Torrez K, Horák-Terra I, Pivello V.   +4 more
europepmc   +1 more source

Long-term Sequelae in Ebola Virus Disease Survivors Receiving Anti-Ebola Virus Therapies in the Democratic Republic of the Congo: A Prospective Cohort Study. [PDF]

Open Forum Infect Dis
Dilu-Keti A, Tovar-Sanchez T, Cuer B, Nkuba-Ndaye A, Mukadi-Bamuleka D, Panzi-Kalunda E, Kitenge-Omasumbu R, Bulabula-Penge J, Mambu-Mbika F, Mbala-Kingebeni P, Ayouba A, Muyembe-Tamfum JJ, Etard JF, Chenge F, Delaporte E, Ahuka-Mundeke S, ‘Les Vainqueurs d’Ebola’ study group .   +16 more
europepmc   +1 more source

Biallelic MYH3 Variants Cause Distal Arthrogryposis in Compound Heterozygosity and a Subclinical Phenotype in Simple Heterozygosity. Codominance or Recessive Inheritance?

Clinical Genetics, EarlyView.
A nuclear family affected by distal arthrogryposis with novel biallelic MYH3 variants, which at the heterozygous state yield a subclinical phenotype, highlighting the complexity of MYH3‐related disorders and their inheritance modes. ABSTRACT Distal arthrogryposis constitutes a highly heterogeneous group of disorders with a critical need for clear ...
Omar Zgheib, Thomas Rio‐Frio, Michel Guipponi, Thierry Nouspikel, Siv Fokstuen, Marc Abramowicz, Philippe Khau Van Kien   +6 more
wiley   +1 more source

Author Correction: Draft genome and description of Merdibacter massiliensis gen.nov., sp. nov., a new bacterium genus isolated from the human ileum. [PDF]

Sci Rep
Anani H, Abdallah RA, Chelkha N, Fontanini A, Ricaboni D, Mailhe M, Raoult D, Fournier PE.   +7 more
europepmc   +1 more source

Expanding the Phenotypic Spectrum Associated With Loss‐of‐Function SMARCA4 Variants to Eye Developmental Anomalies

Clinical Genetics, EarlyView.
This study expands the clinical spectrum of SMARCA4 by describing a novel phenotype in three unrelated individuals with truncating variants. Distinct from Coffin–Siris syndrome and rhabdoid tumor predisposition, this new association is characterized by ocular malformations, specifically microphthalmia and coloboma.
Bertrand Chesneau, Marjolaine Willems, Abdelhakim Bouazzaoui, Léopoldine Lequeux, Julie Plaisancié, Salima El Chehadeh, Hélène Dollfus, Nicolas Chassaing   +7 more
wiley   +1 more source

Partnership for health promotion as a platform to improve public health outcomes in Small Island Developing States: a case study of the Union of the Comoros. [PDF]

Front Public Health
Luciani A, Abega S, Diarra A, Drameh P, Moeti M.   +4 more
europepmc   +1 more source

Assessment of ecosystem status in Mozambique and implications for environmental planning

Conservation Science and Practice, EarlyView.
We assess Mozambique's terrestrial ecosystems using the IUCN Red List of Ecosystems framework, showing that more than half of Mozambique's ecosystems are threatened, with impacts primarily concentrated in temperate subhumid grasslands and pyric tussock savannas.
Kendall R. Jones, Mervyn Lötter, Hugo M. Costa, Gautam Surya, Vanessa Rathbone, Hermenegildo Matimele, Eleutério Duarte, Tereza Alves, Célia Macamo, Denise Nicolau, Muri G. Soares, Roberto Zolho, Hedley S. Grantham   +12 more
wiley   +1 more source