Results 201 to 210 of about 16,318,448 (302)

Synergistic Dual d-Band Engineering at the Ru-N₄/MXene Interface for High-Efficiency and Long-Lived Li-CO₂ Batteries. [PDF]

Angew Chem Int Ed Engl
Tian X, Liu H, Liu H, Cao B, Cui H, Xu B.   +5 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Bidirectional catalysts with dual-atom dynamic d-band centre modulation and support self-reconstruction for de/hydrogenation in MgH₂/Mg. [PDF]

Nat Commun
Jin J, Zhang J, Zhang J, Chen X, Qian H, Jia B, Liu J, Han B, Wang W, Yan X, Yan Y, Shui J, Huang J.   +12 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Sabatier-Adjusted d-Band Centers of Scalable Asymmetric Iron Sites toward Dynamic Nonradical Network for Fast Mineralization with Low-Amount Oxidant. [PDF]

Adv Sci (Weinh)
Chen Y, Jiang X, Pan Z, Li Z, Chen C, Li C, Luo C, Zhang S, Lin D, Xu X, Xu J.   +10 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Electron Transfer-Tailored D-Band Center to Boost Nanozyme Catalysis for Interpretable Machine Learning-Empowered Intelligent Biosensing. [PDF]

Adv Sci (Weinh)
Li Y, Ji C, Cui Z, Feng J, Zhang L, Liu S, Zhang W, Ji Y, Shen Y, Wang J.   +9 more
europepmc   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

A Wideband D-Band Frequency Sextupler Chain with High Harmonic Rejection in 100 nm GaAs pHEMT Technology. [PDF]

Micromachines (Basel)
Wang P, Chen Z, Guo Y, Qi Y, Yang P.
europepmc   +1 more source