Results 201 to 210 of about 20,350,092 (291)

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Electronegativity-Guided Site Differentiation in High-Entropy Alloy for pH-Universal Hydrogen Evolution Reactions. [PDF]

Angew Chem Int Ed Engl
Wu Y, Wang S, Cheong S, He L, Chang CW, Feng Z, Sun CJ, Zhao C.   +7 more
europepmc   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Efficient power generation near room temperature in earth-abundant thermoelectric tin sulfide via lattice ordering. [PDF]

Nat Commun
Fakhri MY, Ghosh A, Lai WC, Nguyen DL, Jheng HH, Valiyaveettil SM, Ganesan P, Sankar R, Huang CY, Chang CC, Cheng CM, Liao CN, Chen BC, Wu HJ, Yang ZL, Chiu YP, Lee MH, Chu MW, Sato S, Hayashi K, Prestipino C, Guilmeau E, Chen LC, Chen KH.   +23 more
europepmc   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Magnetic Moments in Single-Atom Alloys: Trends, Mechanisms, and Implications for Tunable Adsorption. [PDF]

ACS Phys Chem Au
Zhang S, Riviere CI, Montemore MM.
europepmc   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Predicting the photovoltaic and optoelectronic potentials of eco-friendly kesterites Ag₂PdMX₄ (M = Sn, Ge; X = S, Se) through first-principles calculations. [PDF]

RSC Adv
Ullah I, Khan N, Aldosari E, Khan AA, Yildirim Y, Khan I.   +5 more
europepmc   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Millimeter-Scale, Atomically Controlled 2D Topological Insulators Revealed by Multimodal Spectroscopy. [PDF]

ACS Nano
Lee W, Gao Q, Zhao Y, Li H, Tsui A, Zhang Y, Bai Y, Lin H, Nguyen KD, Berruto G, Yan G, Dang J, Wu T, Rokni H, Marchese TS, Meng YS, Liu CX, Zhang XX, Liu C, Huang PY, Hersam MC, Yan B, Yang S.   +22 more
europepmc   +1 more source