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Systematic Evaluation of a Mouse Model of Aging-Associated Parkinson’s Disease Induced with MPTP and D-Galactose [PDF]
BiologyParkinson’s disease (PD) is a common neurodegenerative disorder characterized by motor dysfunction and non-motor symptoms, including cognitive decline. Animal models that replicate PD’s clinical features are essential for therapeutic research. The widely
Tongzheng Liu +11 more
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D-galactose Intake Alleviates Atopic Dermatitis in Mice by Modulating Intestinal Microbiota
Frontiers in Nutrition, 2022 Atopic dermatitis (AD) is one of the most prevalent, chronic and persistent inflammatory skin diseases closely associated with intestinal microbiota. To evaluate the effect of D-galactose intake on AD, we orally administered D-galactose to BALB/c mice ...
Dong-Yeon Kim +13 more
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D-Galactose Induces Chronic Oxidative Stress and Alters Gut Microbiota in Weaned Piglets
Frontiers in Physiology, 2021 Oxidative stress commonly occurs in pig production, which can severely damage the intestinal function of weaned piglets. This study was conducted to investigate the effects of D-galactose with different levels used to induce chronic oxidative stress on ...
Hui Han +19 more
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Antioxidants, 2022 The prevalence of age-related cognitive impairment is increasing as the proportion of older individuals in the population grows. It is therefore necessary and urgent to find agents to prevent or ameliorate age-related cognitive impairment ...
Ying Gao, Yongquan Xu, Junfeng Yin
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Anti-Aging Effect of Chitosan Oligosaccharide on d-Galactose-Induced Subacute Aging in Mice [PDF]
Marine Drugs, 2018 Chitosan oligosaccharide (COS), a natural polysaccharide with good antioxidant and anti-inflammatory properties, is the depolymerized product of chitosan possessing various biological activities. The present study was designed to investigate the possible
Songzhi Kong +9 more
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Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2019 BACKGROUND AND OBJECTIVE: Aging is accompanied with low concentration of testosterone hormone and apoptosis induction in the testis. The aim of this research was to investigate the effects of different doses of curcumin as the active ingredient of ...
M Yousefi +3 more
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Frontiers in Bioengineering and Biotechnology, 2020 D-Galactose-specific L-arabinose isomerase (L-AI) would have much potential for the enzymatic conversion of D-Galactose into D-tagatose, while most of the reported L-AIs are L-arabinose specific.
Guoyan Zhang +5 more
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D-(+)-Galactose-induced aging: A novel experimental model of erectile dysfunction.
PLoS ONE, 2021 Erectile dysfunction (ED) is defined as the inability to achieve and/or maintain penile erection sufficient for satisfactory sexual relations, and aging is one of the main risk factors involved.
Mathania Silva de Almeida Rezende +12 more
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Mediators of Inflammation, 2020 Inflammation and oxidative stress play key roles in the process of aging and age-related diseases. Since serine availability plays important roles in the support of antioxidant and anti-inflammatory defense system, we explored whether serine deficiency ...
Fengen Wang +5 more
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PLoS ONE, 2017 Animal models are commonly used in brain ageing research. Amongst these, models where rodents are exposed to d-galactose are held to recapitulate a number of features of ageing including neurobehavioral and neurochemical changes.
Saeed Sadigh-Eteghad +5 more
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