Results 81 to 90 of about 19,968,253 (257)

The Hawking cascades of gravitons from higher-dimensional Schwarzschild black holes

open access: yesPhysics Letters B, 2016
It has recently been shown that the Hawking evaporation process of (3+1)-dimensional Schwarzschild black holes is characterized by the dimensionless ratio η≡τgap/τemission≫1, where τgap is the characteristic time gap between the emissions of successive ...
Shahar Hod
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Séminaire GAP: SAVOIRS ET IDEOLOGIES EN POLITIQUE

open access: yes, 2012
SAVOIRS ET IDEOLOGIES EN POLITIQUE Genèse, circulation, transmission Programme 2012-13 Un Mercredi par Mois, de 14h à 16h — Bâtiment F Université Paris Ouest Nanterre — Plan du Campus 14 novembre 2012 : Jean-Louis Fournel (Paris 8), autour de l’ouvrage ...
gap
core  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Positivity of the Veneziano amplitude in ten dimensions

open access: yesJournal of High Energy Physics
The Veneziano amplitude describing the tree-level scattering of four open superstrings is expected to be consistent with unitarity in ten spacetime dimensions.
Gareth Mansfield
doaj   +1 more source

Effectiveness Of The Core Activation And Rehabilitation Exercises For Knee Osteoarthritis - Program (CARE -KOA©) Among Patients Diagnosed With Knee Osteoarthritis. [version 4; peer review: 2 approved]

open access: yesF1000Research
Background Knee osteoarthritis (KOA) is a prevalent condition. Recent research highlights the role of kinetic chain and core muscle involvement in disease progression, yet evidence for structured core activation protocols such as CARE-KOA© remains ...
Saurabh Mehta   +5 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Gap functions for quasi-variational inequalities

open access: yes, 2006
Gap functions for quasi-variational inqualities, or "linearized" quasi-variational inequalities, in Banach spaces, are presented.
LIGNOLA, MARIA BEATRICE
core  

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