Results 81 to 90 of about 19,968,253 (257)
The Hawking cascades of gravitons from higher-dimensional Schwarzschild black holes
It has recently been shown that the Hawking evaporation process of (3+1)-dimensional Schwarzschild black holes is characterized by the dimensionless ratio η≡τgap/τemission≫1, where τgap is the characteristic time gap between the emissions of successive ...
Shahar Hod
doaj +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Séminaire GAP: SAVOIRS ET IDEOLOGIES EN POLITIQUE
SAVOIRS ET IDEOLOGIES EN POLITIQUE Genèse, circulation, transmission Programme 2012-13 Un Mercredi par Mois, de 14h à 16h — Bâtiment F Université Paris Ouest Nanterre — Plan du Campus 14 novembre 2012 : Jean-Louis Fournel (Paris 8), autour de l’ouvrage ...
gap
core
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Positivity of the Veneziano amplitude in ten dimensions
The Veneziano amplitude describing the tree-level scattering of four open superstrings is expected to be consistent with unitarity in ten spacetime dimensions.
Gareth Mansfield
doaj +1 more source
Background Knee osteoarthritis (KOA) is a prevalent condition. Recent research highlights the role of kinetic chain and core muscle involvement in disease progression, yet evidence for structured core activation protocols such as CARE-KOA© remains ...
Saurabh Mehta +5 more
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Gap functions for quasi-variational inequalities
Gap functions for quasi-variational inqualities, or "linearized" quasi-variational inequalities, in Banach spaces, are presented.
LIGNOLA, MARIA BEATRICE
core

