Results 171 to 180 of about 24,770,333 (307)

YÜKSELTİLMİŞ D-OPTİMAL DİZAYN YÖNTEMİ KULLANILARAK MÜHENDİSLİK DİZAYNLARINDA ETKİNLİĞİN GELİŞTİRİLMESİ: ‘SENTETİK JET’ DİZAYN OPTİMİZASYON ÇALIŞMASI

open access: yesHavacılık ve Uzay Teknolojileri Dergisi, 2007
The purpose of this study is to study the efficiency of several “design of experiments” (DOE) approaches used for the analysis and optimization of engineering designs.
Fatih Erdoğan
doaj  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Mechanism-constrained D-optimal design of a flexible claw for peanut shelling under biological variability. [PDF]

open access: yesFront Plant Sci
Tuo Y   +11 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

On the Equivalence of Optimality Design Criteria for the Placebo-Treatment Problem [PDF]

open access: yes
We consider a class of optimality criteria and show that each crite- rion has its unique and equivalent dual within the class. This property can be used to find a variety of optimal designs, including a class of compound optimal designs and their ...
Zhu, Wei, Dette, Holger, Wong, Weng Kee
core  

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

OPTIMAL EXPORT POLICY IN THE PRESENCE OF R&D INVESTMENT [PDF]

open access: yes
The purpose of this paper is to analyze the optimal export policy in a two-stage game in which a domestic and a foreign firm compete in price and R&D investment.
Tsuyoshi Toshimitsu
core  

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