Results 191 to 200 of about 16,379,393 (306)

A Randomized Basket Trial Design for Dose Optimization Based on Bayesian Model Averaging Using Spike-and-Slab Priors. [PDF]

Stat Med
Yimer BB, Takeda K.
europepmc   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

A Comparison of Item Selection Methods and Parameter Estimation Approaches for Online Calibration in Computerized Adaptive Testing. [PDF]

Educ Psychol Meas
Ertuna L, Glas CAW, Atar B.
europepmc   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

Optimizing Clinical Study Designs for CAR-T Cell Therapy: Development of an Efficient Sampling Strategy Through Optimal Experimental Design. [PDF]

CPT Pharmacometrics Syst Pharmacol
Klima F, Mc Laughlin AM, Michelet R, Huisinga W, Haussmann K, Künkele A, Hooker AC, Kloft C.   +7 more
europepmc   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

Physics-Aware Machine-Learning-Driven Inverse Design of Broadband Ultra-Open Acoustic Metamaterials. [PDF]

Adv Sci (Weinh)
Yang Z, Li M, Xie X, Chen A, Bifano TG, Zhang X.   +5 more
europepmc   +1 more source

D-optimal designs for parameter estimation for indirect pharmacodynamic response models. [PDF]

J Pharmacokinet Pharmacodyn, 2009
Khinkis LA, Krzyzanski W, Jusko WJ, Greco WR.   +3 more
europepmc   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Effects of Structural Designs on the Accuracy, Dimensional Stability, and Material Consumption of Digital Light Processing-Printed Models. [PDF]

Int Dent J
Liu H, Wang J, Zhao Y, Zhang Y, Kou J, Zhang Q, Li K, Wu Y.   +7 more
europepmc   +1 more source