The role of circular RNAs in regulating cytokine signaling in cancer
FEBS Open Bio, EarlyView.Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi +4 more
wiley +1 more source
Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies
FEBS Open Bio, EarlyView.Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa +13 more
wiley +1 more source
Estimation of optimal serum concentrations of 25-hydroxyvitamin D for multiple health outcomes
, 2006 Heike A. Bischoff‐Ferrari +4 more
openalex +1 more source
Learning and fine-tuning a generic value-selection heuristic inside a constraint programming solver. [PDF]
ConstraintsMarty T +6 more
europepmc +1 more source
Identifying prognostic targets in metastatic prostate cancer beyond AR
FEBS Open Bio, EarlyView.Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng +13 more
wiley +1 more source
Cost-effective and optimal control analysis for mitigation strategy to chocolate spot disease of faba bean. [PDF]
Sci RepAlemneh HT, Molla AE, Makinde OD.
europepmc +1 more source
Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies
Aging and Cancer, EarlyView.This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal +8 more
wiley +1 more source
Equidistant and D-optimal designs for parameters of Ornstein–Uhlenbeck process
, 2007 Jozef Kiseľák, Milan Stehlík
openalex +2 more sources
UAV Path Optimization for Angle-Only Self-Localization and Target Tracking Based on the Bayesian Fisher Information Matrix. [PDF]
Sensors (Basel)Dogancay K, Hmam H.
europepmc +1 more source