Results 271 to 280 of about 24,603 (322)

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Multi-stage bidirectional informed-RRT * plant protection UAV path planning method based on A * algorithm domain guidance. [PDF]

Front Plant Sci
Li J, Gao Y, Li Z, Zhang W, Yu W, Hu Y, Liu H, Li C.   +7 more
europepmc   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Nutrient availability increases photosynthetic capacity without altering the cost of resource use for photosynthesis. [PDF]

AoB Plants
Lankhorst JA, de Boer HJ, Behling DC, Drake PL, Perkowski EA, Rebel KT.   +5 more
europepmc   +1 more source

On Optimality of d + 1 TI Shared Functions of 8 Bits or Less.

, 2020
Dušan Božilov
openalex   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Order of Addition in Mixture-Amount Experiments. [PDF]

Pharm Stat
Hasan T, Ahmad T.
europepmc   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Association between the motor optimality score-revised and clinical variables of preterm infants. [PDF]

BMC Pediatr
Apaydın U, Altunalan T.
europepmc   +1 more source

Dried blood spot card cardiometabolic profile of young adults identified within optimal range (green), or outside optimal range, i.e., at risk (red) for a) total cholesterol (mg/dL), b) HDL-cholesterol (mg/dL), c) LDL-cholesterol (mg/dL), d) VLDL-cholesterol (mg/dL).

Katherine M. Livingstone (9735919), Kathleen M. Dullaghan (21716260), Jeffrey M. Craig (7410239), Barbara Brayner (13302897), Sarah A. McNaughton (8622846)   +4 more
openalex   +1 more source