Artificial Intelligence‐Guided Phenotypic Drug Repurposing Against Streptococcus pneumoniae
Advanced Science, EarlyView.Integrated artificial intelligence (AI) ensembles identify highly potent repurposed drugs against Streptococcus pneumoniae. Prospective virtual screening of 6747 drugs uncovers nine active candidates, including thiostrepton. This drug exhibits low picomolar potency and bypasses established resistance in multidrug‐resistant strains, demonstrating an ...
Joshua S. Fitch +6 more
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São Pedro, uma Igreja do Brasil no Egito
Revista de História, 1966 O Brasil e o Egito, dois países tão distantes, mas que, em virtude do interêsse de D. Pedro II, pela terra dos Faraós, tornaram-se espiritualmente próximos no que diz às tradições é ao seu passado. Estão em hemisférios opostos, mas em latitudes idênticas,
Dom Carlos Tasso de Saxe-Coburgo e Bragança
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Reminiscências da primeira mestra de d. Pedro II: Mariana Carlota de Verna
Revista Educação em Questão, 2022 O estudo aborda a trajetória de Mariana Carlota de Verna como primeira mestra de d. Pedro II, e o que a levou, posteriormente, a receber o título de condessa de Belmonte. O objetivo central é evidenciar as circunstâncias em que assumiu o cargo de preceptora do herdeiro do trono do Brasil e algumas das dificuldades que enfrentou para se manter nele até ...
Maria Celi Chaves Vasconcelos +1 more
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A Drug‐Gated, Modular STAb‐T Immunotherapy With External Control
Advanced Science, EarlyView.Engineered STAb‐TON cells act as programmable living factories that continuously secrete inactive antibody modules, which assemble extracellularly into a functional T cell engager only upon small‐molecule administration. This externally controlled platform enables reversible, on‐demand regulation of antitumor immunity, establishing a new paradigm for ...
Susana Luengo‐Arias +23 more
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Unveiling a Near‐Total Rear Passivation for High Performance of Ultra‐Thin ACIGS
Advanced Science, EarlyView.Ultra‐thin solar cells of (Ag,Cu)(In,Ga)Se2 (ACIGS) suffer from rear interface recombination, limiting their performance. To tackle it, a full coverage plasma enhanced chemically vapor‐deposited 8 nm porous SiOx passivation layer was implemented and evaluated. It is shown that a combination of the near‐complete passivation from silica and the formation
Xavier L. Pinheiro +7 more
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Giant Direct Magnetoelectric Effect in Nanocomposite CoFe2O4:PVDF‐TrFE Thin Films
Advanced Science, EarlyView.A novel three‐step grow‐etch‐fill fabrication approach creates structured cobalt ferrite/ferroelectric polymer nanocomposites with high interfacial areas. Driven by efficient strain‐mediated coupling, this crystalline system achieves a giant room‐temperature magnetoelectric coefficient nearly two orders of magnitude higher than other CFO/PVDF‐TrFE thin
Muireann de h‐Óra +8 more
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Arquivo Maaravi: Revista Digital de Estudos Judaicos da UFMG, 2009 Este artigo aborda a visita de Sua Majestade o Imperador do Brasil D. Pedro II (1825-1891) a uma loja de antiguidades em Jerusalém. A visita a Terra Santa aconteceu em 1876 durante a segunda viagem do dignitário brasileiro ao exterior.
Reuven Faingold
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The Interplay of Curvature, Geometry, and Topology Shapes Tissue Organisation in Epithelial Shells
Advanced Science, EarlyView.Purely geometric 3D Voronoi models predict the organisation of epithelial shells. The interplay of curvature, geometry, and topology enriches the number of pentagons in shells with lower number of cells. Small MDCK cysts and Mouse embryos match the top polygonal configurations in a compactness‐based ranking derived from the Voronoi model. In conclusion,
Laura Morato +9 more
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Nos trilhos da civilização: preâmbulos das disputas técnico-científicas na estrada de ferro de D. Pedro II (1850-1855): On the tracks of civilization: preambles of the technical scientific disputes in the D. Pedro II railway (1850-1855) [PDF]
The article investigates the preambles of the technical-scientific disputes surrounding the creation of the D. Pedro II Railway (1850-1855), highlighting the role of railways as symbols of civilization and modernity in Imperial Brazil.
Mesquita de Monteiro Marinho, Pedro Eduardo +1 more
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La Gramatica Griega escrita en lengua Castellana : para que dende luego puedan los niños aprender la lengua griega juntamente con la latina conforme al consejo de Quintiliano con el aiuda i fauor de la vulgar [PDF]
Esta Gramática griega, impresa en Zaragoza, aparece normalmente junto con la Gramática griega, impresa en Madrid por Pedro Madrigal en el año 1587Copia digital. Madrid : Ministerio de Cultura. Subdirección General de Coordinación Bibliotecaria, 2008Sign.:
Simón Abril, Pedro, ca. 1530- ca. 1595
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