Results 111 to 120 of about 232,754 (286)
Aggressive prostate cancer is associated with pericyte dysfunction
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
wiley +1 more source
Systemic Crisis in the US-Turkish Relations Under the Presidency of D. Trump
Relations between the United States and Turkey, the two military-political allies of the North Atlantic Treaty Organization (NATO), are experiencing an unprecedented crisis in their history.
A. A. Davydov
doaj +1 more source
The problem of future contingents: scoping out a solution [PDF]
Various philosophers have long since been attracted to the doctrine that future contingent propositions systematically fail to be true—what is sometimes called the doctrine of the open future.
Todd, Patrick
core
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Global Competitiveness Potential of U.S. Nuclear Energy Technologies
The new Trump administration considers the U.S. nuclear energy industry as one of the most important and promising tools for maintaining the country’s global leadership in the international arena.
T. V. Voronin
doaj +1 more source
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Do Foreign Nationals Really Have Constitutional Rights? [PDF]
[Excerpt] Last month, President Trump issued an executive order that has become known as the travel ban. Among other things, the ban sought to temporarily exclude from the United States foreign nationals from seven predominantly Muslim countries ...
Greabe, John M.
core +60 more sources
Until recently, social media was seen to promote democratic discourse on social and political issues. However, this powerful communication platform has come under scrutiny for allowing hostile actors to exploit online discussions in an attempt to ...
Badawy, Adam +2 more
core +1 more source

