Results 61 to 70 of about 12,759 (308)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
X-linked retinoschisis maculopathy treated with topical dorzolamide, and relationship to genotype.
, 2011 Topical dorzolamide may have some effect in reducing central macular thickness in patients with XLRS, but this does not necessarily correlate with improvement in VA.
A J Lotery +7 more
core +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Is America’s Trump, South Asia’s loss? [PDF]
, 2016 The victory of Donald Trump was not anticipated in most of South Asia. But here he is, as the next American president. While some people here are in shock and others are demonizing him, we need to coldly calculate what his victory means for us.
Suba Chandran, D
core
, 2018 Signaling through the vitamin D receptor has been shown to be biologically active and important in a number of preclinical studies in prostate and other cancers.
Donald L Trump, Jeanny B Aragon-Ching
core +1 more source
Variants in the vitamin D pathway, serum levels of vitamin D, and estrogen receptor negative breast cancer among African-American women: A case-control study [PDF]
, 2012 Introduction: American women of African ancestry (AA) are more likely than European Americans (EA) to have estrogen receptor (ER)-negative breast cancer. 25-hydroxyvitamin D (25OHD) is low in AAs, and was associated with ER-negative tumors in EAs.
Ademuyiwa, F +18 more
core +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Журнал Фронтирных ИсследованийThe American national identity was formed largely under the influence of the frontier phenomenon and, in particular, the harsh natural conditions in which the “first settlers” found themselves.
Zhanna G. Konovalova
doaj +1 more source
EU-Turkey Relations under the D. Trump Administration: a Quick “Warming” [PDF]
Современная ЕвропаThe article examines the evolution of relations within the Turkey-US-EU triangle after Donald Trump's return to the White House. During the first half of 2025, there was a significant increase in Turkey's role in the geopolitical landscape in the Eastern
Alexander Shumilin
doaj +1 more source