Results 151 to 160 of about 153,579 (216)

Using multilabel classification neural network to detect intersectional DIF with small sample sizes

British Journal of Mathematical and Statistical Psychology, EarlyView.
Abstract This study introduces InterDIFNet, a multilabel classification neural network for detecting intersectional differential item functioning (DIF) in educational and psychological assessments, with a focus on small sample sizes. Unlike traditional marginal DIF methods, which often fail to capture the effects of intersecting identities and require ...
Yale Quan, Chun Wang
wiley   +1 more source

To vary or not to vary: A flexible empirical Bayes factor for testing variance components

British Journal of Mathematical and Statistical Psychology, EarlyView.
Abstract Random effects are the gold standard for capturing structural heterogeneity, such as individual differences or temporal dependence. Yet testing their presence is difficult because variance components are constrained to be non‐negative, creating a boundary problem. This paper introduces a flexible empirical Bayes factor (EBF) for testing random
Fabio Vieira, Hongwei Zhao, Joris Mulder
wiley   +1 more source

Male response to sex pheromone emission in Mediterranean populations of the long-tailed mealybug (Hemiptera: Pseudococcidae). [PDF]

J Insect Sci
Castro A, Vacas S, Gavara A, García-García V, Navarro I, Navarro-Llopis V.   +5 more
europepmc   +1 more source

Preclinical models for evaluating psychedelics in the treatment of major depressive disorder

British Journal of Pharmacology, EarlyView.
Psychedelic drugs have seen a resurgence in interest as a next generation of psychiatric medicines with potential as rapid‐acting antidepressants (RAADs). Despite promising early clinical trials, the mechanisms which underlie the effects of psychedelics are poorly understood.
Laith Alexander, Dasha Anderson, Luke Baxter, Matthew Claydon, James Rucker, Emma S. J. Robinson   +5 more
wiley   +1 more source

Characterizing functional connectivity gradients for the hippocampus-amygdala complex in healthy and psychiatric cohorts. [PDF]

Brain Struct Funct
Liu XS, Vrijsen JN, Yan L, Haak KV, Collard RM, van Eijndhoven PFP, Beckmann CF, Fernández G, Tendolkar I, Kohn N.   +9 more
europepmc   +1 more source

Psychedelics as pharmacotherapeutics for substance use disorders: A scoping review on clinical trials and perspectives on underlying neurobiology

British Journal of Pharmacology, EarlyView.
Theorized mechanism of dopamine homeostasis restoration in the nucleus accumbens core induced by a psychedelic intervention. Abstract Psychedelics have garnered great attention in recent years as treatments for major depressive disorder (MDD) and treatment‐resistant depression because of their ability to alter consciousness and afflicted cognitive ...
Lucas Wittenkeller, Gary Gudelsky, T. John Winhusen, Davide Amato   +3 more
wiley   +1 more source

Phase separation of PGL-3 driven by structured domains that oligomerize and interact with RGG motifs. [PDF]

EMBO Rep
Kuroiwa R, Sharma P, Putnam AA, Fried SD, Seydoux G.   +4 more
europepmc   +1 more source

An intracellular recombinant single‐chain variable antibody fragment as a new class of phosphodiesterase type 5 inhibitors

British Journal of Pharmacology, EarlyView.
Background and Purpose Cyclic guanosine monophosphate (cGMP) is a ubiquitous second messenger involved in human (patho‐)physiology. Phosphodiesterase 5 (PDE5) is a major cGMP hydrolyzing enzyme in many cell types including vascular smooth muscle cells (VSMCs). Several highly selective PDE5 inhibitors are in clinical use. However, there are currently no
Kürsat Kirkgöz, Sophie Sprenger, Olga Schweigert, Sanika Mohagaonkar, Matti Walsdorff, Tanja Zeller, Filip Berisha, Viacheslav O. Nikolaev, Sergei D. Rybalkin   +8 more
wiley   +1 more source

Clinical nuclear medicine applications of zirconium-89 immuno-PET: a comprehensive review from a radiopharmaceutical perspective. [PDF]

EJNMMI Radiopharm Chem
Dubois J, Deshayes E, Kucharczak F, Cadet MM, Zhou J, Paunet T, Fersing C.   +6 more
europepmc   +1 more source

Endothelium‐ and epithelium‐derived novel endogenous catecholamines as modulators of the autonomic nervous system

British Journal of Pharmacology, EarlyView.
Abstract Catecholamines are classically viewed as neuronal transmitters and adrenal hormones; however, accumulating evidence demonstrates that sources other than nerve fibres and adrenal medulla play a fundamental role in local organ regulation. Physiological paradoxes, such as preserved organ function after denervation or transplantation, challenge a ...
Mariana G. de Oliveira, Edson Antunes, Fabiola Zakia Monica, Gilberto De Nucci   +3 more
wiley   +1 more source