Results 61 to 70 of about 132,827 (252)

Intensive first-line FIr-C/FOx-C association of triplet chemotherapy plus cetuximab in wild-type metastatic colorectal cancer patients: preliminary phase II data and prediction of individual limiting toxicity syndromes by pharmacogenomic biomarkers

Therapeutic Advances in Medical Oncology, 2019
Background: Intensive triplet chemotherapy/bevacizumab significantly increased metastatic colorectal cancer (MCRC) outcome. This phase II study investigated the safety/activity of FIr-C/FOx-C triplet/cetuximab (CET) in first-line RAS wild-type and the ...
Gemma Bruera, Silvia Massacese, Francesco Pepe, Umberto Malapelle, Antonella Dal Mas, Eugenio Ciacco, Giuseppe Calvisi, Giancarlo Troncone, Maurizio Simmaco, Enrico Ricevuto   +9 more
doaj   +1 more source

Immunohistochemical prognostic markers of esophageal squamous cell carcinoma: a systematic review

Chinese Journal of Cancer, 2017
Background Esophageal squamous cell carcinoma (ESCC) is an aggressive malignancy, with a high incidence and poor prognosis. In the past several decades, hundreds of proteins have been reported to be associated with the prognosis of ESCC, but none has ...
Chunni Wang, Jingnan Wang, Zhaoli Chen, Yibo Gao, Jie He   +4 more
doaj   +1 more source

An elastic segment of the whisker shaft enables coding of the whisking phase via whisker torsion in rats and mice

The Anatomical Record, EarlyView.
An elastic segment was found in the basal part of the whisker shaft in rats and mice. Application of force to the whisker bulb of isolated follicles caused bending and twisting of this segment. Active whisker movements deform this segment, causing whisker shaft deflection and selective activation of mechanoreceptors at different phases of whisking ...
Sebastian Haidarliu, Guy Nelinger, Luka Gantar, Ehud Ahissar, Inbar Saraf‐Sinik   +4 more
wiley   +1 more source

Conditions for collective action: Understanding factors supporting and constraining community-based fish culture in Bangladesh, Cambodia and Vietnam [PDF]

, 2011
Flood-prone ecosystems in South and Southeast Asia are traditionally farmed with deepwater rice followed by post-flood rice culture during the dry season. During the flood season, the same land is inundated, creating an open-access water body subject to
Joffre, Olivier M., Sheriff, N.
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Structure of the Multiphase Chalcolithic Tell Chiselet–Grădiștea Fundeanca (Romania) From SH‐Wave Full‐Waveform Inversion, Borehole Geophysics and Coring

Archaeological Prospection, EarlyView.
ABSTRACT The emergence and development of settlement mounds, also called tells, is of major interest for the analysis of socio‐economic transformations occurring in the lower Danube plain during the East European Chalcolithic period. In this context, the multiphase chronology and structural layout of tells are highly relevant indicators, but small ...
Manuel Zolchow, Daniel Köhn, Natalie Pickartz, Martin Thorwart, Adrian Serbanescu, Ercan Erkul, Dennis Wilken, Stefan Dreibrodt, Robert Hofmann, Johannes Müller, Catalin Lazar, Wolfgang Rabbel   +11 more
wiley   +1 more source

Community-based fish culture in seasonal floodplains and irrigation systems [PDF]

, 2011
The overall objective of the project was to enhance fish production from seasonally flooding areas and irrigation systems using a collective approach to fish culture.
Barman, B.K., Brakel, Martin L. van, Haque, A.B.M.M., Hong, M.C., Joffre, Olivier M., Kodio, A., Nguyen, H. van, Rahman, F., Russell, A., Sheriff, N., Valmonte-Santos, Rowena A., Werthmann, C., Zhu, J.   +12 more
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Harnessing nanomaterials to precisely regulate the immunosuppressive tumor microenvironment for enhanced immunotherapy

BMEMat, EarlyView.
The immunosuppressive tumor microenvironment, characterized by hypoxia, redox imbalance, elevated interstitial fluid pressure, and acidity, was comprehensively elucidated. This review discussed the etiology and consequences of the characteristics of the immunosuppressive tumor microenvironment, and analyzed the recent advancements in nanomaterials for ...
Wen Zhang, Xueyin Hu, Wei Cheng, Lumeng Zhang, Yuanfang Chen, Qinrui Fu, Luntao Liu, Saijun Fan   +7 more
wiley   +1 more source

Sustainability Solution: Renewable Energy Innovation Against Climate Disasters

Business Strategy and the Environment, EarlyView.
ABSTRACT In an era where climate change poses profound threats to human life and activities, the need for innovative renewable energy solutions has never been more critical. Accordingly, this study examines the moderating effects of natural disaster uncertainty and climate policy uncertainty on firms' pursuit of renewable energy innovation following ...
Hiva Rastegar, Aymen Sajjad, Gabriel Eweje, Kazunori Kobayashi   +3 more
wiley   +1 more source

The Development of the Human Female Reproductive Tract: Part 2—Vagina

Clinical Anatomy, EarlyView.
ABSTRACT Urogenital epithelium replaces the original paramesonephric (Müllerian) epithelium in the human fetal vagina. We re‐investigated this cell replacement histologically and with three‐dimensional reconstructions. In the lesser pelvis, both Müllerian ducts fuse to form the uterovaginal canal.
Cindy J. M. Hülsman, S. Eleonore Köhler, Gabriela Morosan‐Puopolo, Jill P. J. M. Hikspoors, Wouter H. Lamers   +4 more
wiley   +1 more source

Genetic analyses of the fusion protein genes in human parainfluenza virus types 1 and 3 among patients with acute respiratory infections in Eastern Japan from 2011 to 2015 [PDF]

, 2017
弘前大学博士（保健学）2011年から2015年にかけて、東日本における急性呼吸器感染症（ARI）患者から検出されたヒトパラインフルエンザウイルス1型（HPIV1,1668nt）および3型（HPIV3,1620nt）の融合タンパク質遺伝子（F遺伝子）の全長を解析した。最尤法を用いて系統樹を構築し、遺伝的距離（p-distance）およびpositive selection site および negative selection sites を解析した ...
筒井, 理華
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