Results 161 to 170 of about 153,405 (278)

A "Function-First" Approach to Identify Regulatory T cell-Targeting Antibodies for Immunotherapy. [PDF]

Cancer Immunol Res
Cleary KLS, Semmrich M, Martensson L, Tornberg UC, Ermert D, Taylor MC, Oldham RJ, Dadas O, Buckingham JF, Kim J, Chan HTC, Palm A, Fischer AH, Boden M, Mattsson J, Holmkvist P, Lim SH, Beers SA, Frendeus B, Teige I, Cragg MS.   +20 more
europepmc   +1 more source

Women in business: Gender and commercial space in nineteenth‐century Glasgow

The Economic History Review, EarlyView.
Abstract Focusing on women entrepreneurs in a large British city, we examine how women's commercially listed businesses populated that city. Using commercial property rental records, our study allows us to understand sectoral variation and the distribution of businesses across the city and to assess both the absolute and relative contribution of women ...
Graeme Acheson, Gill Newton, Linda Perriton   +2 more
wiley   +1 more source

Outcomes of a third course of salvage spine stereotactic radiosurgery for spinal metastases: a single-institution case series. [PDF]

J Neurooncol
Bai JJ, Balagamwala EH, Magnelli A, Angelov L, Suh JH, Murphy ES, Pendyala P, Chao ST.   +7 more
europepmc   +1 more source

Loncastuximab Tesirine in Relapsed/Refractory Diffuse Large B‐Cell Lymphoma: Evidence and Practical Guidance From Italian Clinical Experience

European Journal of Haematology, EarlyView.
ABSTRACT Patients with relapsed/refractory (R/R) diffuse large B‐cell lymphoma (DLBCL) who progress to the third‐line setting face a lack of standardized treatment, despite the presence of multiple available therapies. In this context, antibody–drug conjugates represent a relatively new class of anticancer agents; among them, loncastuximab tesirine is ...
Francesca Bonello, Andrea Aroldi, Alessia Castellino, Lara Mannelli, Elia Boccellato, Serena Rosati, Luisa Verga, Umberto Vitolo   +7 more
wiley   +1 more source

Verification of a Fluid-Structure Interaction Model for Aortic Stenosis Through Comparison With In Vitro Experiments. [PDF]

Int J Numer Method Biomed Eng
Verstraeten S, Meiburg R, Janssens K, Hoeijmakers M, Karajan N, Rutten M, Veer MV, Tonino P, van de Vosse F, Huberts W.   +9 more
europepmc   +1 more source

Alterations of bone proteins in medication‐related osteonecrosis of the jaw

European Journal of Oral Sciences, Volume 133, Issue 2, April 2025.
Abstract Changes in the protein expression pattern of osteoblastic lineage cells from the alveolar bone (OLAB) during medication‐related osteonecrosis of the jaw (MRONJ) have rarely been investigated. This lack of information is partly because of the limited availability of healthy samples and the lack of human alveolar bone cell lines for research ...
Andrea Schubert, Phillipp Brockmeyer, Philipp Kauffmann, Jan Wiegel, Florian Lautenbacher, Nicolai Miosge, Boris Schminke   +6 more
wiley   +1 more source

Phytogenic feed additive mitigates necrotic enteritis-associated gut damage and performance loss in broilers. [PDF]

Poult Sci
Khairunnesa M, Kumar A, Wu SB, Akter S, Barekatain R, Palanisamy K, Gharib-Naseri K.   +6 more
europepmc   +1 more source

Regulation of PHOX2B gene expression by the long non‐coding natural antisense RNA PHOX2B‐AS1

The FEBS Journal, EarlyView.
PHOX2B is a transcription factor essential for autonomic nervous system development. We identify and characterize PHOX2B‐AS1, a human long non‐coding antisense transcript at the PHOX2B locus, along with its murine counterpart. Our findings reveal bidirectional transcription and reciprocal regulation: PHOX2B activates PHOX2B‐AS1, whereas PHOX2B‐AS1 ...
Simona Di Lascio, Ana Lucia Cuadros Gamboa, Martina Bertocchi, Filippo Chiesa, Francesca Cargnin, Ettore Mosca, Paride Pelucchi, Viviana Tritto, Stefania Corti, Isabella Ceccherini, Paola Riva, Roberta Benfante, Diego Fornasari   +12 more
wiley   +1 more source

Designer RNA nanostructures co-transcribed and self-assembled inside human cell nuclei. [PDF]

Nat Commun
Chang X, Jeziorek M, Yang Q, Bonder EM, Yan H, Etchegaray JP, Zhang F.   +6 more
europepmc   +1 more source

Anti‐cancer drugs targeting the NADH‐binding site of VDAC rewire channel electrophysiology and partially suppress cation selectivity

The FEBS Journal, EarlyView.
VA molecules alter VDAC1 gating by increasing anion flow and reducing cation permeability. In cancer cells, which rely on ER‐mitochondria Ca2+ transfer and overexpress VDAC1, this imbalance triggers bioenergetic stress, ROS buildup, and mitochondrial collapse, leading to cell death.
Stefano Conti‐Nibali, Giuseppe Battiato, Salvatore Antonio Maria Cubisino, Cristina Arrigoni, Marco Lolicato, Simona Reina, Vito De Pinto   +6 more
wiley   +1 more source