Results 191 to 200 of about 1,456,482 (281)

Beyond Transconductance: Cell‐Polymer Coupling Determines Fidelity in Action Potential Recording via Electrolyte‐Gated Polymer Transistors

open access: yesAdvanced Science, EarlyView.
High electrical performance alone does not guarantee efficient bioelectronic signal transduction. Despite excellent mixed ionic‐electronic conduction, recordings from cardiomyocytes reveal that p(g2T‐TT)‐based OECTs predominantly transduce field potential FP‐like signals due to weak cell‐polymer coupling.
Giulia Zoe Zemignani   +10 more
wiley   +1 more source

Density of Blood and Lymphatic Vessels in Stretch Marks: A Preliminary Study. [PDF]

open access: yesIn Vivo
Piotrowska A   +6 more
europepmc   +1 more source

Correction of the FI Results in H┣D2∞┫D2 Control and Parameterization of H┣D2∞┫D2 state Feedback

open access: yesCorrection of the FI Results in H┣D2∞┫D2 Control and Parameterization of H┣D2∞┫D2 state Feedback
identifier:oai:t2r2.star.titech.ac.jp ...
openaire  

Development and Structural Characterization of UTE‐156, a Covalent Inhibitor of the VCP/p97 AAA+ ATPase

open access: yesAdvanced Science, EarlyView.
The AAA+ ATPase Valosin‐containing protein (VCP/p97) regulates protein homeostasis by unfolding ubiquitinated substrates. Here, we describe UTE‐156, a novel irreversible covalent inhibitor that modifies Cys522 in the D2 ATPase motor domain. Although its pharmacochemical limitations preclude immediate therapeutic use, UTE‐156 serves as a valuable ...
Daniela Tamayo‐Jaramillo   +8 more
wiley   +1 more source

From Design to Prototype: High‐Sensitivity Tri‐Mode Operation Photodetectors Based on 1T‐2H Hybrid MoS2

open access: yesAdvanced Science, EarlyView.
This work demonstrates a phase‐engineered MoS2 photodetector that dynamically switches among photocapacitive (PCC), photovoltaic (PV), and photoconductive (PC) modes. By transforming the traditionally parasitic capacitance into an active signal source, the device achieves self‐powered, high‐sensitivity detection with a fast response of 19.2 ms, and a ...
Xinyu Li   +16 more
wiley   +1 more source

Dual Aptamers‐Based SETDB1 PROTACs as Effective Anti‐Tumor Strategies for Breast Cancer

open access: yesAdvanced Science, EarlyView.
This study establishes dual‐aptamer PROTACs targeting SETDB1 using a SETDB1‐specific aptamer conjugated to AS1411. The designed PROTACs penetrate cells, recruit MDM2 to degrade SETDB1, and inhibit cancer cell proliferation and migration. Remarkably, they also overcome tamoxifen resistance and enhance CD8+ T cell cytotoxicity, suppressing tumor growth ...
Yanxuan Guo   +6 more
wiley   +1 more source

Superconductivity Transition above 70K in (Pb┣D2(1+x)/2┫D2Cu┣D2(1-x)/2┫D2)(Sr┣D21-y┫D2Ca┣D2y┫D2)┣D22┫D2(Y┣D21-x┫D2Ca┣D2x┫D2)Cu┣D22┫D2O┣D2z┫D2

open access: yesSuperconductivity Transition above 70K in (Pb┣D2(1+x)/2┫D2Cu┣D2(1-x)/2┫D2)(Sr┣D21-y┫D2Ca┣D2y┫D2)┣D22┫D2(Y┣D21-x┫D2Ca┣D2x┫D2)Cu┣D22┫D2O┣D2z┫D2
identifier:oai:t2r2.star.titech.ac.jp ...
openaire  

Ultrathin‐Gold‐Resonators‐Enabled Bolometers with High Linearity, Responsivity, and Repeatability

open access: yesAdvanced Science, EarlyView.
This work demonstrates ultrathin gold nanomechanical resonators operating in HF/VHF bands, unveiling their potential for laser power sensing. By exploiting frequency shifts resulting from laser‐induced thermal tension, these devices can function as sensitive nanoscale bolometers, with outstanding linearity, responsivity, and repeatability. The findings
Jiaqi Wu   +9 more
wiley   +1 more source

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