Results 271 to 280 of about 542,594 (321)

Characterizing fucoxanthin as a selective dopamine D3/D4 receptor agonist: Relevance to Parkinson's disease.

Chemico-Biological Interactions, 2019
Fucoxanthin and fucosterol are archetypal lipid components of edible brown algae that provide several health benefits. Lately, their protective role in Aβ1-42-induced cognitive dysfunction in animal models has been reported (Alghazwi et al., 2019; Oh et ...
Pradeep Paudel, S. Seong, H. Jung, J. Choi   +3 more
semanticscholar   +1 more source

Octamethylcyclotetrasiloxane (D4)

Toxicology and Industrial Health, 2016
Octamethylcyclotetrasiloxane (D4; CAS No. 556-67-2) is used as a monomer in the manufacture of polymeric materials, which are widely used in various industrial and/or medical applications, such as breast implants. D4 has a relatively low order of toxicity following acute administration via the oral, dermal, and inhalation routes of exposure and is not
openaire   +2 more sources

Dopamine D4 receptor ubiquitination

Biochemical Society Transactions, 2016
Ubiquitination is a post-translational modification that targets proteins for degradation but can also regulate other cellular processes such as endocytosis, trafficking and DNA repair. We investigate ubiquitination of the dopamine D4 receptor (D4R) which belongs to the superfamily of G protein-coupled receptors (GPCR).
Kamila, Skieterska, Pieter, Rondou, Kathleen, Van Craenenbroeck   +2 more
openaire   +2 more sources

Polymorphism in Sulfanilamide-d4

Journal of Pharmaceutical Sciences, 1970
Thermal behaviors of four crystalline forms of sulfanilamide and of sulfanilamide-d4 have been examined. Heats of transition and fusion have been determined. The deuterated modifications exhibit smaller heats of transition and heats of fusion than the corresponding undeuterated forms. There is, however, a difference in the magnitude of this decrease in
H O, Lin, J K, Guillory
openaire   +2 more sources

Stereocontrolled total synthesis of Resolvin D4 and 17(R)-Resolvin D4

Organic & Biomolecular Chemistry, 2023
We describe the stereocontrolled synthesis of Resolvin D4 and 17(R)-Resolvin D4. These molecules possess protective activities in resolving inflammation.
Robert Nshimiyimana, Stephen J. Glynn, Charles N. Serhan, Nicos A. Petasis   +3 more
openaire   +2 more sources

(22S)-hydroxyvitamin D4

Journal of the Chemical Society, Perkin Transactions 1, 1973
Using ergosterol acetate as starting material, 22-hydroxylated analogues of 22,23-dihydroergosterol have been prepared via(i) selective epoxidation of the 22,23-double bond and (ii) Grignard reaction on the hexanor-22-aldehyde. (22S)-Hydroxyvitamin D4, produced upon irradiation of (22S)-22,23-dihydro-22-hydroxyergosterol, showed no significant ...
Douglas R. Crump, Dudley H. Williams, Bohumil Pelc   +2 more
openaire   +1 more source

D4 — Etudes dentaires

Nouvelles archives du Muséum d'histoire naturelle de Lyon, 1987
L'étude céphalométrique confirme les caractères observés directement : — profil arciforme, — prédominance de l'étage inférieur de la face, — forte saillie du bouton mentonnier. Avec un indice facial de 92,8, la face est considérée comme étroite, de type leptoprosope.
openaire   +2 more sources

Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine

Nature, 1991
H. V. Tol, J. Bunzow, H. Guan, R. Sunahara, P. Seeman, H. Niznik, O. Civelli   +6 more
semanticscholar   +1 more source

Supervision D4

2023
Howard B. Levine, Gisèle de Mattos Brito, José Américo Junqueira de Mattos   +2 more
openaire   +1 more source

Return of D4 Dopamine Receptor Antagonists in Drug Discovery.

Journal of Medicinal Chemistry, 2017
C. Lindsley, C. Hopkins
semanticscholar   +1 more source