Results 11 to 20 of about 14,534 (118)

Human otopathology in scleroderma

open access: yesLaryngoscope Investigative Otolaryngology, Volume 8, Issue 6, Page 1657-1665, December 2023., 2023
Scleroderma is a complex chronic progressive immune‐mediated disease. To date, there is a lack of information about how middle and inner ear may be affected by this disorder. Herein we described three otopathology cases of patients with scleroderma onset during life.
Melissa Castillo‐Bustamante   +4 more
wiley   +1 more source

Oncolytic viral therapy as promising immunotherapy against glioma

open access: yesMedComm – Future Medicine, Volume 2, Issue 4, December 2023., 2023
Multiple preclinical experiments and clinical trials have shown that oncolytic viruses (OVs) exhibit good antitumor activity in treating gliomas. This article summarizes the crucial clinical progress of various OVs in the treatment of glioma, the challenges faced by OVs in the treatment of glioma, and looks forward to the future development prospects ...
Die Hu   +7 more
wiley   +1 more source

A creative place‐making framework – Story‐creation for a sustainable development

open access: yesSustainable Development, Volume 31, Issue 5, Page 3673-3691, October 2023., 2023
Abstract Sustainable development is the ultimate goal for policy‐makers and place‐makers to develop a place. Nevertheless, although many approaches, such as exogenous, endogenous, neo‐endogenous, creative cities, and creative place‐making, have been studied, realizing a place‐based approach requires further research.
Siow‐Kian Tan, Siow‐Hooi Tan
wiley   +1 more source

Blockade of endogenous insulin receptor signaling in the nucleus tractus solitarius potentiates exercise pressor reflex function in healthy male rats

open access: yesThe FASEB Journal, Volume 37, Issue 9, September 2023., 2023
During exercise the brainstem integrates sensory information from skeletal muscle afferents and arterial baroreceptors, resulting in controlled increases in blood pressure. The influence of central insulin signaling on the exercise pressor reflex (EPR) is undetermined.
Juan A. Estrada   +8 more
wiley   +1 more source

Discovery of a bifunctional xylanolytic enzyme with arabinoxylan arabinofuranohydrolase‐d3 and endo‐xylanase activities and its application in the hydrolysis of cereal arabinoxylans

open access: yesMicrobial Biotechnology, Volume 16, Issue 7, Page 1536-1547, July 2023., 2023
1. A novel bifunctional xylanolytic enzyme (rAbf43A) was obtained.2. rAbf43A exhibits arabinoxylan arabinofuranohydrolase‐d3 and endo‐xylanase activities.3. rAbf43A shows obvious synergy with cognate bifunctional xylanase/feruloyl esterase. Abstract Xylanolytic enzymes, with both endo‐xylanase and arabinoxylan arabinofuranohydrolase (AXH) activities ...
Ruonan Wang   +4 more
wiley   +1 more source

New insights on the catalytic center of proteins from peptidylprolyl isomerase group based on the FOD‐M model

open access: yesJournal of Cellular Biochemistry, Volume 124, Issue 6, Page 818-835, June 2023., 2023
Abstract Generating the structure of the hydrophobic core is based on the orientation of hydrophobic residues towards the central part of the protein molecule with the simultaneous exposure of polar residues. Such a course of the protein folding process takes place with the active participation of the polar water environment.
Irena Roterman   +2 more
wiley   +1 more source

Inequality, Redistribution, and the Financial Crisis: Evidence from Distributional National Accounts for Austria

open access: yesReview of Income and Wealth, Volume 69, Issue 1, Page 195-227, March 2023., 2023
In this paper, we provide novel findings regarding the distributional effects of the global financial and economic crisis and how redistribution operated during this time, using detailed data for Austria. We construct distributional national accounts for the period 2004–2016 by combining survey data, tabulated tax data, and detailed national accounts ...
Stefan Jestl, Emanuel List
wiley   +1 more source

Gaussian process regression and classification using International Classification of Disease codes as covariates

open access: yesStat, Volume 12, Issue 1, January/December 2023., 2023
Abstract In electronic health records (EHRs) data analysis, nonparametric regression and classification using International Classification of Disease (ICD) codes as covariates remain understudied. Automated methods have been developed over the years for predicting biomedical responses using EHRs, but relatively less attention has been paid to ...
Sanvesh Srivastava   +4 more
wiley   +1 more source

Efficacy and Field Safety of Ilunocitinib for the Control of Allergic Dermatitis in Client‐Owned Dogs: A Multicenter, Double‐Masked, Randomised, Placebo‐Controlled Clinical Trial

open access: yesVeterinary Dermatology, Volume 36, Issue 6, Page 825-837, December 2025.
Background: Inhibition of the Janus kinase pathway is an established treatment for allergic dermatitis. Objective: To evaluate the efficacy and safety of ilunocitinib for control of pruritus in dogs with allergic dermatitis in a randomised, double‐masked clinical trial.
Sophie Forster   +5 more
wiley   +1 more source

Reduced Muscle Force in Dystrophic DMDΔ52 Pigs Is Incompletely Restored by Systemic Transcript Reframing (DMDΔ51–52)

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 5, October 2025.
ABSTRACT Background Duchenne muscular dystrophy (DMD) is a fatal X‐linked disease caused by mutations in the DMD gene, leading to dystrophin deficiency and progressive degeneration of skeletal and cardiac muscles. Pigs lacking DMD exon 52 (DMDΔ52) are a clinically severe model for DMD, mimicking molecular, functional and pathological hallmarks of the ...
Michaela Blasi   +17 more
wiley   +1 more source

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