Results 21 to 30 of about 2,492 (188)
A thriving healthcare system perfectly reflects economic development and contentment amongst the people of any region. With increasing anxiety concering health and growing medical needs, hospitals worldwide face substantial challenge to provide patients ...
Dev Manimay, Kumar Dinesh, Mor Rahul S.
doaj +1 more source
Conformational Trajectory of the Molecular Chameleon Grazoprevir From Formulation to Target-Bound. [PDF]
ABSTRACT Macrocycles represent a promising class of beyond‐rule‐of‐5 (bRo5) therapeutics, capable of targeting proteins traditionally considered undruggable by conventional small molecules. Macrocycles exhibit intrinsic flexibility and often display a “chameleon‐like” ability to adapt to their environment, thereby enhancing their oral bioavailability ...
Wieske LHE +5 more
europepmc +2 more sources
Side chain χ1 torsion angle sampling of active site residues (H57, D81, S139) as a function of Ficoll crowder distances.
Michael Feig (775637) +2 more
core +1 more source
Forecasting Cinema Attendance at the Movie Show Level: Evidence from Poland
Background: Cinema programmes are set in advance (usually with a weekly frequency), which motivates us to investigate the short-term forecasting of attendance.
Baranowski Paweł +2 more
doaj +1 more source
Sampling of side chain center distances between active site residues (H57, D81, S139) in water and when crowders or substrates are in close contact.
Michael Feig (775637) +2 more
core +1 more source
Loss aversion, overconfidence of investors and their impact on market performance evidence from the US stock markets [PDF]
Purpose – The current study aims to investigate the impacts of two behavioral biases, namely, loss aversion and overconfidence on the performance of US companies.
Ahmed Bouteska, Boutheina Regaieg
doaj +1 more source
Catalysis-relevant distances between active site residues (H57:Nδ-H … Oδ1/2-D81 and H57-Nε … HOγ-S139) as a function of Ficoll crowder distances.
Michael Feig (775637) +2 more
core +1 more source
Background: Owing to the heaviness of setbacks and shocks companies frequently face from the internal/external business environment, building solid organizational resilience and shifting towards strategic sustainability have become the top demands in ...
Ahmić Azra
doaj +1 more source
The distance was calculated to any of active site residues in simulations without (top row) and with (bottom row) substrates. In the crystal structure (4JMY), the values of the χ1 torsion are 76.6° for H57, -161.4° for D81, and -82.6° for S139.
Michael Feig (775637) +2 more
core +1 more source
Consumers Engagement Toward Food Brands – The Case of Dairy Products
Research background: As food markets continue to develop the role and position of food consumers evolve as well. Food producers redefine their market strategies and focus on creating loyalty, building good contacts and consumers’ engagement towards ...
Gazdecki Michał +1 more
doaj +1 more source

