Results 111 to 120 of about 34,593,801 (261)

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Comparative study of three types of technology fee system for R&D performance under government R&D projects

Journal of Intellectual Property
Prior to the enactment of the National Research And Development Innovation Act, there were no definitions of key terms related to national R&D, which made it difficult for the public, including researchers, to clearly understand national R&D.
JaeHoon Lee
doaj   +1 more source

Oral history interview with Robert D. Schmidt

, 1983
Transcript not available electronically. Please contact CBI.Schmidt discusses the history of marketing computer systems at Control Data Corporation.Schmidt, R. D. (Robert D.). (1983). Oral history interview with Robert D. Schmidt.
Schmidt, R. D. (Robert D.)
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Vitamin D, Tissue Resistance, Bone Mineral Density and Breast Cancer Risk [PDF]

, 2009
Etiologic factors such as vitamin D and estrogen are potentially related to breast cancer development, although details of their mechanisms are not completely understood. We prospectively investigated correlates of breast cancer risk among postmenopausal
Albano, Jessica
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Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

D. P. Juravskyi: the First Ukrainian Theorist of Statistical Science (in memory of the 160th anniversary of his death)

Статистика України, 2016
The contribution to the development of statistical science of the prominent Ukrainian theorist-statistician of the first half of XIX century Dmytro Petrovych (1810-1856) is discussed. It is emphasized that D.
Е. V. Chekotovskyi
doaj  

Battle flags hanging in Ohio History Center plaza

, 1970
Photograph of Ohio's Battle Flag collection hanging in the plaza of the Ohio History Center in Columbus, Ohio, ca. 1970. The flags were displayed on the Center’s plaza level from the time the building opened in 1970 through the late 1980s, when they were
Ohio History Connection
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Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Plaque to Director General Robert D. Havener

, 1985
Plaque to Director General Robert D. Havener from D.

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