FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Short communication: performance of beef cows fed Kernza intermediate wheatgrass straw mixed with alfalfa haylage. [PDF]
Transl Anim SciPizarro DM +3 more
europepmc +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Evolutionary Antifragile Therapy Is a Treatment Strategy to Suppress Drug Resistance by Exploiting Dose-Response Convexity. [PDF]
Cancer ResWest J +6 more
europepmc +1 more source
Structured Value Elimination with D-Separation Analysis
, 2010 In the last ten years, new models based on Bayesian Net- works (BN) emerged to handle large and complex systems. These new models can be divided in two: the unification with First Order Logic and uncertainty (Markov Logic Networks, Bayesian Logic) and Knowledge Base Construction Mod- els (Probabilistic Relational Models, Multy-Entity Bayesian Networks,
Torti, Lionel, Wuillemin, Pierre-Henri
openaire +2 more sources
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Perceptions of the value of higher education among undergraduate students
A rising tide of reports, commentaries, surveys, and studies seems to herald a crisis in higher education – a crisis frequently framed as a question of value.
Beit-Arie, Yali
core
Wild Barley Exhibits Higher Phosphorus-Use Efficiency and Greater Rhizosheath Carboxylates Than Cultivated Barley Under Low-Phosphorus Conditions. [PDF]
Physiol PlantTao Y +7 more
europepmc +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Prostate cancer: Value of the PI-FAB score and volume-adjusted PSA density in recurrence assessment after HIFU. [PDF]
Eur J Radiol OpenElsner C +9 more
europepmc +1 more source