Results 241 to 250 of about 314,050 (303)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Association Between Maternal Diet and Frequency of Micronuclei in Mothers and Newborns: A Systematic Review. [PDF]

Nutrients
Araújo AC, Nascimento PKDSBD, Medeiros MCS, Bortolin RH, Cobucci RN, Rezende AA.   +5 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Bronchial Atresia Presenting With Recurrent Pneumonia in an Adult With Asthma: The Importance of Post-infectious Radiological Reassessment. [PDF]

Cureus
Carneiro G, Aranha R, Macedo B.
europepmc   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

No associations between HIV reservoir and inflammation in long-term virally suppressed dolutegravir-based ART-treated individuals. [PDF]

Front Immunol
Fombellida-Lopez C, Aguilar Ortmans D, Moutschen M, Pasternak AO, Darcis G.   +4 more
europepmc   +1 more source

Rapid and reagent-free screening of occult hepatitis B virus infection based on plasma Vis-NIR spectral pattern recognition. [PDF]

Front Bioeng Biotechnol
Huang L, Huang X, Xia J, Huang L, Zhou H, Chen M, He B, Chen M, Mo Q, Pan T, Ou C.   +10 more
europepmc   +1 more source

"Autonomy & Management in Prison Nursing". Development and validation of a mobile application. [PDF]

Invest Educ Enferm
Diniz Alves L, Vieira Guimarães L, Almeida da Silva L, do Carmo Cruz Robazzi ML, Savada NO, de Souza Terra F, Marques Dos Santos SV.   +6 more
europepmc   +1 more source

Structures of two LarA-like nickel-pincer nucleotide cofactor-utilizing enzymes with a single catalytic histidine residue. [PDF]

Protein Sci
Gatreddi S, Subramanian S, Sui D, Wang T, Urdiain-Arraiza J, Desguin B, Hausinger RP, Parent KN, Hu J.   +8 more
europepmc   +1 more source

HBV Catch-up Vaccination in Children and Adults with Incomplete or Unknown Vaccination to Reduce Hepatitis B-related Morbidity: A Systematic Review. [PDF]

Acta Med Philipp
Gregorio GEV, Velasco-Aro SJG.
europepmc   +1 more source