Results 101 to 110 of about 35,844 (219)

Intravenous Thrombolysis in Patients Taking Direct Oral Anticoagulation Treatment Before Stroke Onset: Results from the Safe Implementations of Treatments in Stroke International Stroke Registry

Annals of Neurology, Volume 97, Issue 6, Page 1205-1214, June 2025.
Objectives Intravenous thrombolysis (IVT) is contraindicated for acute ischemic stroke (AIS) patients taking direct oral anticoagulants (DOACs) within 48 hours before index stroke. Limited data exist on off‐label use of IVT for these patients. We compared the safety and outcomes of IVT in AIS patients with DOAC treatment and patients with no OAC before
Marius Matusevicius, Malin Säflund, Maurizio Balestrino, Manuel Cappellari, Delfina Ferrandi, Abdoreza Ghoreishi, André Peeters, Viiu‐Marika Rand, Manuela De Michele, Aleksandras Vilionskis, Andrea Zini, Niaz Ahmed   +11 more
wiley   +1 more source

Real‐World Health Care Resource Utilization and Costs Associated With First‐Line Dronedarone Versus First‐Line Ablation in Adults With Atrial Fibrillation

Clinical Cardiology, Volume 48, Issue 6, June 2025.
A retrospective, observational, claims‐based cohort study identified that over 24‐months follow‐up of patients recently diagnosed with AF, a strategy of first‐line dronedarone was associated with similar or lower rates of any outpatient or inpatient visits, and lower total payer costs compared with an ablation‐based approach. ABSTRACT Background Rhythm
Stephen J. Greene, Samantha Schilsky, Andrew W. Roberts, Shaum M. Kabadi, David S. McKindley, Ron Preblick, Jason Rashkin, Reno C. Leeming, Renee M. Sajedian, Andrea M. Russo   +9 more
wiley   +1 more source

UPLC-MRM Mass Spectrometry Method for Measurement of the Coagulation Inhibitors Dabigatran and Rivaroxaban in Human Plasma and Its Comparison with Functional Assays.

PLoS ONE, 2015
IntroductionThe fast, precise, and accurate measurement of the new generation of oral anticoagulants such as dabigatran and rivaroxaban in patients' plasma my provide important information in different clinical circumstances such as in the case of ...
Joachim Kuhn, Tatjana Gripp, Tobias Flieder, Marcus Dittrich, Doris Hendig, Jessica Busse, Cornelius Knabbe, Ingvild Birschmann   +7 more
doaj   +1 more source

The effect of new oral anticoagulants and extended thromboprophylaxis policy on hip and knee arthroplasty outcomes: observational study [PDF]

, 2015
The efficacy and safety of the new oral anticoagulants (NOAC) and the benefits of extended duration thromboprophylaxis following hip and knee replacements remain uncertain.
Aylin, P, Bottle, A, Loeffler, M, Oragui, E, Pinder, E   +4 more
core   +2 more sources

Pitfalls in Argatroban Monitoring: Heparin Interference With Dilute Thrombin Time Assays

International Journal of Laboratory Hematology, EarlyView.
Agathe Herb, Jordan Wimmer, Laurent Mauvieux, Laurent Sattler   +3 more
wiley   +1 more source

Design and rationale of the eLym™ System for Decompensation of Excess Lymphatic Fluid via the Thoracic Duct in Acute Heart Failure (DELTA‐HF)

ESC Heart Failure, Volume 12, Issue 3, Page 1719-1726, June 2025.
Abstract Aims The interstitial space is the major compartment in which the excess fluid is located, forming peripheral congestion in acute decompensated heart failure (ADHF). The lymphatic system is responsible for the constant drainage of the compartment.
Jan Biegus, JoAnn Lindenfeld, G. Michael Felker, George Bakris, Michael Jonas, Anuradha Lala, Zviad Kereselidze, George Khabeishvili, Irakli Gogorishvili, Julio Núñez, Antoni Bayés‐Genís, Piotr Ponikowski, William T. Abraham   +12 more
wiley   +1 more source

Reducing Hemorrhagic Complication by Dabigatran Via Neurovascular Protection After Recanalization With Tissue Plasminogen Activator in Ischemic Stroke of Rat [PDF]

, 2013
This study assesses the risks and benefits of tissue plasminogen activator (tPA) treatment under oral anticoagulation with dabigatran compared with warfarin or vehicle control in transient middle cerebral artery occlusion (tMCAO). After pretreatment with
Abe, Koji, Deguchi, Kentaro, Ikeda, Yoshio, Kono, Syoichiro, Kurata, Tomoko, Omote, Yoshio, Yamashita, Toru, Yunoki, Taijun   +7 more
core   +1 more source

Antithrombotic and anticoagulant effects of the direct thrombin inhibitor dabigatran, and its oral prodrug, dabigatran etexilate, in a rabbit model of venous thrombosis [PDF]

, 2007
Wolfgang Wienen, J M Stassen, Henning Priepke, Uwe J. Ries, Norbert Hauel   +4 more
openalex   +1 more source

Efficacy and safety of non‐vitamin K antagonist oral anticoagulants versus warfarin in atrial fibrillation and kidney failure under hemodialysis: A meta‐analysis of controlled randomized trials

Journal of Arrhythmia, Volume 41, Issue 3, June 2025.
Rivaroxaban or apixaban is as safe and effective as VKAs in patients with AF and kidney failure with hemodialysis. Even on oral anticoagulants, these patients remain at high risk of cardiovascular events and all‐cause mortality. Integrated care and holistic management are important for this high‐risk population. Abstract Background Atrial fibrillation (
Ting‐Yung Chang, Yi‐Hsin Chan, Tze‐Fan Chao, Chin‐Yu Lin, Yenn‐Jiang Lin, Shih‐Lin Chang, Li‐Wei Lo, Yu‐Feng Hu, Fa‐Po Chung, Shih‐Ann Chen   +9 more
wiley   +1 more source

Re-evaluating Safety and Effectiveness of Dabigatran Versus Warfarin in a Nationwide Data Environment: A Prevalent New-User Design Study

Drugs - Real World Outcomes, 2019
Introduction The new user cohort design is widely used to assess the effects of a new drug, such as dabigatran, but inherently excludes some users due to prior use of the comparator drug, for example warfarin.
Hui-Min Diana Lin, Chao-Lun Lai, Yaa-Hui Dong, Yu-Kang Tu, K. Arnold Chan, Samy Suissa   +5 more
doaj   +1 more source