Results 101 to 110 of about 28,958 (244)
Background It is difficult to evaluate adequate dose of heparin for cardiopulmonary bypass (CPB) by activated clotting time (ACT) in a patient receiving both heparin and dabigatran because dabigatran can also prolong ACT.
Yu Kawada +4 more
doaj +1 more source
Background. Atrial fibrillation (AF) increases the risk of having stroke as high as five fold. Anticoagulant administration such as vitamin K antagonist has been used regularly to reduce the occurence of stroke.
Alvin Nursalim, Yoga Yuniadi
doaj +1 more source
Eline A, Dubois, Adam F, Cohen
openaire +2 more sources
Importance Uninterrupted dabigatran therapy reduces stroke risk in patients with nonvalvular atrial fibrillation (NVAF) undergoing ablation and is associated with a lower bleeding risk than uninterrupted warfarin therapy.
A. Nogami +13 more
semanticscholar +1 more source
ABSTRACT Purpose Nursing home (NH) residents are at high risk for major bleeding and are frequently exposed to complex medication regimens that may increase the likelihood of clinically important drug–drug interactions (DDIs). However, DDI evidence from community‐dwelling populations may not generalize to NH residents, and real‐world signals involving ...
Adam M. D'Amico +9 more
wiley +1 more source
Bioresorbable Scaffolds for Coronary Arteries: Where Do We Stand Today?
Bioresorbable coronary scaffolds are moving from thick strut pitfalls to thinner, stronger, healing‐oriented designs. Integrating advances in materials, guided implantation with preparation, size, and postdilation steps, and resorption aligned to healing, we synthesize clinical evidence and chart a roadmap toward intelligent, transient platforms ...
Junya Matsuda +5 more
wiley +1 more source
Using Pharmacovigilance Data for Signal Detection of Drug Interactions for Rosuvastatin
ABSTRACT The 3‐hydroxy‐3‐methyl‐glutaryl‐coenzyme A reductase inhibitor rosuvastatin is a substrate of breast cancer resistance protein (BCRP). BCRP inhibition increases rosuvastatin plasma concentrations and may result in concentration‐dependent muscle toxicity, at worst rhabdomyolysis.
Ronja Levomäki +3 more
wiley +1 more source
Exploring Risks of Adverse Drug Events From Single Drug to Three‐Drug Combination
ABSTRACT Use of three‐drug combinations is common and could increase the risk of adverse drug events (ADEs). Signals of ADEs from three‐drug combinations could be identified from real‐world data, and the risks of ADEs from single drug exposure to three‐drug combination exposure could be illustrated by a graphic model.
Yi Shi +14 more
wiley +1 more source
Idarucizumab for Dabigatran Reversal — Full Cohort Analysis
C. Pollack +20 more
semanticscholar +2 more sources
ABSTRACT Aim The aim of this all‐case post‐marketing study was to evaluate the real‐world safety and effectiveness in all children and adolescents with chronic hepatitis C with or without compensated cirrhosis treated with glecaprevir/pibrentasvir (G/P) in Japan. Methods This prospective, observational post‐marketing surveillance study was conducted at
Tatsuki Mizuochi +6 more
wiley +1 more source

