Results 131 to 140 of about 48,696 (305)

Coagulation and anticoagulation in idiopathic pulmonary fibrosis [PDF]

, 2015
Idiopathic pulmonary fibrosis (IPF) is an incurable, progressive interstitial lung disease with a prognosis that is worse than that of many cancers. Epidemiological studies have demonstrated a link between IPF and thrombotic vascular events.
Crooks, Michael G., Hart, Simon P.
core   +3 more sources

IgG and IgM Anti‐Phosphatidylserine/Prothrombin Complex Antibody Detection May Improve Classification Accuracy of Systemic Lupus Erythematosus and Antiphospholipid Antibody Syndrome

ACR Open Rheumatology, Volume 7, Issue 10, October 2025.
Objective Antiphospholipid antibody (aPL) syndrome (APS) classification requires a thrombotic event and detection of lupus anticoagulant (LAC), anticardiolipin antibodies (aCL), or anti–β2‐glycoprotein I (anti‐β2GPI) antibodies on two occasions ≥12 weeks apart. Here, we investigated the utility of anti–phosphatidylserine/prothrombin complex (anti‐PS/PT)
Christina Donath, Sara Kahlown, Liye Suo, Katalin Banki, Andras Perl   +4 more
wiley   +1 more source

The Role of Genetics in Stroke Risk and Outcome: A Review of Current Evidence

Brain and Behavior, Volume 15, Issue 10, October 2025.
This study delineates the multiple pathways leading to stroke, encompassing genetic risk factors such as lipid/cholesterol metabolism, blood pressure regulation genes, and endothelial dysfunction. The report includes genetic pathways such as Val66Met polymorphism, prothrombin G20210A, interleukin‐6 and tumor necrosis factor gene variant, along with ...
Mega Obukohwo Oyovwi, Benneth Ben‐Azu, Ejayeta Jeroh, Faith B. Friday   +3 more
wiley   +1 more source

Reduced Versus Full‐Dose Direct Oral Anticoagulants for Venous Thromboembolism in Cancer Patients: A Systematic Review and Meta‐Analysis

eJHaem, Volume 6, Issue 5, October 2025.
ABSTRACT Background Venous thromboembolism (VTE) is a serious complication in cancer patients, with malignancy increasing the risk significantly. Direct oral anticoagulants (DOACs) have emerged as a convenient alternative to traditional therapies, though optimal dosing remains uncertain.
Danyal Bakht, Muhammad Arham, Zarwa Rashid, Maaz Amir, Zarish Nasir, Mustabeen Zahra Naqvi, Maleeha Tahir, Musab Khalil, Esha Gulzar, Hafiz Muhammad Haris, Kinza Bakht, Allah Dad, Haseeb Tareen, Muhammad Numan Awais   +13 more
wiley   +1 more source

Dabigatran for catastrophic antiphospholipid syndrome

Blood Coagulation & Fibrinolysis, 2019
: Vitamin K antagonists (VKA) remain the treatment of choice for catastrophic antiphosphilipid syndrome (CAPS). However, when VKAs do not work for a specific patient, direct oral anticoagulants (DOAC) may be a valid therapeutic alternative. We present a patient with a psychiatric disorder and CAPS who was noncompliant to VKA and low-molecular-weight ...
Marc Sorigue, Mireia Santos-Gomez, Manuel Monreal, Cristian Morales-Indiano, Alejandro Olivé, Elisa Orna, Edurne Sarrate   +6 more
openaire   +5 more sources

Restarting Oral Anticoagulation in Patients With Atrial Fibrillation After Admission for a Gastrointestinal Bleeding Event: Effectiveness and Safety of Direct Oral Anticoagulants Compared to Warfarin

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 45, Issue 10, Page 638-653, October 2025.
ABSTRACT Background There are sparse data to guide resumption of direct oral anticoagulants (DOACs) versus warfarin in patients with atrial fibrillation (AF) who survive a major gastrointestinal bleeding (GIB) event. Objective To compare the risk–benefit profile of restarting DOACs versus warfarin among patients with AF following hospitalization for ...
Oluwadolapo D. Lawal, Herbert D. Aronow, Fisayomi Shobayo, Yichi Zhang, Anne L. Hume, Tracey H. Taveira, Kelly L. Matson, Justin Gold, Xuerong Wen   +8 more
wiley   +1 more source

Dabigatran for left ventricular thrombus

Indian Heart Journal, 2015
Male patient in dilated phase of hypertrophic cardiomyopathy had multiple hospitalizations during the past 2 years either due to congestive heart failure, stroke, scar epilepsy, or atrial fibrillation and ventricular tachycardia. Medication included evidence based therapy for heart failure, cordarone and warfarin. Anticoagulation had to be discontinued
Satyavan Sharma, Chandrashekhar Munjewar, Satishkumar Suresh Kolekar   +2 more
openaire   +3 more sources

A Multicenter, Open‐Label Study to Assess the Safety of Nebulized Tissue Plasminogen Activator for the Acute Treatment of Pediatric Plastic Bronchitis: The PLATyPuS Trial

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 45, Issue 10, Page 677-687, October 2025.
ABSTRACT Introduction Pediatric plastic bronchitis (PB) is a rare complication of surgically palliated congenital heart disease (CHD). Fibrin casts obstruct airways and can cause respiratory distress. There are no therapeutics approved by the United States Food and Drug Administration to treat PB, but inhaled tissue plasminogen activator (tPA) has been
Kathleen A. Stringer, David Goldberg, Sharon Chen, Philip Thrush, Eric M. Graham, Adam Lubert, Jeffrey Myers, Laura McLellan, Thomas Flott, Samya Nasr, Kurt R. Schumacher   +10 more
wiley   +1 more source

Dabigatran-induced esophagitis

Cleveland Clinic Journal of Medicine, 2019
The tablets contain tartaric acid, and if they get stuck in the esophagus, the acid leaching out can damage the mucosa.
openaire   +3 more sources

Interstitial pneumonia caused by dabigatran

Respiratory Medicine Case Reports, 2018
We describe the case of a 73-year-old man who experienced dry cough and exertional dyspnea after dabigatran administration. Chest radiographs revealed the development of bilateral consolidative and ground glass opacity, and transbronchial lung biopsy showed organized materials in the alveolar spaces with moderate inflammatory infiltrate and focal ...
Toyoshi Yanagihara, Norio Yamamoto, Yasuaki Kotetsu, Naoki Hamada, Eiji Harada, Kunihiro Suzuki, Kayo Ijichi, Yoshinao Oda, Yoichi Nakanishi   +8 more
openaire   +4 more sources