Results 11 to 20 of about 28,958 (244)

Dabigatran Level Before Reversal Can Predict Hemostatic Effectiveness of Idarucizumab in a Real-World Setting

Frontiers in Medicine, 2020
Background: Idarucizumab has been included in guidelines for the management of bleeding or surgical procedure in dabigatran-treated patients without need for biological monitoring.
Nicolas Gendron, Nicolas Gendron, Richard Chocron, Richard Chocron, Paul Billoir, Julien Brunier, Laurence Camoin-Jau, Marie Tuffigo, Dorothée Faille, Dorothée Faille, Dorian Teissandier, Juliette Gay, Juliette Gay, Emmanuelle de Raucourt, Emmanuelle de Raucourt, Ludovic Suner, Corentin Bonnet, Anne-Céline Martin, Anne-Céline Martin, Dominique Lasne, Chayma Ladhari, Aurélien Lebreton, Laurent Bertoletti, Laurent Bertoletti, Nadine Ajzenberg, Nadine Ajzenberg, Pascale Gaussem, Pascale Gaussem, Pierre-Emmanuel Morange, Pierre-Emmanuel Morange, Pierre-Emmanuel Morange, Véronique Le Cam Duchez, Alain Viallon, Pierre-Marie Roy, Pierre-Marie Roy, Agnès Lillo-le Louët, Agnès Lillo-le Louët, David M. Smadja, David M. Smadja, David M. Smadja   +39 more
doaj   +2 more sources

Comparison of the efficacy and safety between rivaroxaban and dabigatran in the treatment of acute portal vein thrombosis in cirrhosis

BMC Gastroenterology, 2023
Background New oral anticoagulants (NOACs) have been becoming prevalent in recent years and are increasingly used in the treatment of port vein thrombosis.
Haonan Zhou, Mingdong Wu, Shixiong Yu, Han Xia, Wu Yu, Kai Huang, Yikuan Chen   +6 more
semanticscholar   +1 more source

Dabigatran versus vitamin K antagonists for atrial fibrillation in clinical practice: final outcomes from Phase III of the GLORIA-AF registry

Clinical Research in Cardiology, 2022
Prospectively collected, routine clinical practice-based data on antithrombotic therapy in non-valvular atrial fibrillation (AF) patients are important for assessing real-world comparative outcomes.
M. Huisman, C. Teutsch, Shihai Lu, Hans-Christoph Diener, S. Dubner, J. Halperin, Chang-Sheng Ma, K. Rothman, Ragna Lohmann, V. K. Gurusamy, D. Bartels, G. Lip   +11 more
semanticscholar   +1 more source

Effects of dabigatran versus warfarin on 2-year cognitive outcomes in old patients with atrial fibrillation: results from the GIRAF randomized clinical trial

BMC Medicine, 2022
Observational studies support a role for oral anticoagulation to reduce the risk of dementia in atrial fibrillation patients, but conclusive data are lacking.
B. Caramelli, P. C. Yu, F. A. Cardozo, I. Magalhães, R. Spera, D. K. Amado, M. C. Escalante-Rojas, D. Gualandro, D. Calderaro, C. Tavares, Flávio A. Borges-Júnior, A. Pastana, M. Matheus, S. Brucki, A. C. Rodrigues, R. Nitrini, P. Caramelli   +16 more
semanticscholar   +1 more source

Direct Thrombin Inhibitor Dabigatran Compromises Pulmonary Endothelial Integrity in a Murine Model of Breast Cancer Metastasis to the Lungs; the Role of Platelets and Inflammation-Associated Haemostasis

Frontiers in Pharmacology, 2022
Activation of the coagulation cascade favours metastatic spread, but antithrombotic therapy might also have detrimental effects on cancer progression. In this study, we characterized the effects of dabigatran, a direct reversible thrombin inhibitor, on ...
M. Smęda, M. Stojak, K. Przyborowski, M. Sternak, Joanna Suraj‐Prażmowska, K. Kuś, K. Derszniak, A. Jasztal, A. Kij, Anna Kurpińska, A. Kieronska-Rudek, K. Wojnar-Lason, E. Buczek, T. Mohaissen, S. Chłopicki   +14 more
semanticscholar   +1 more source

Measurement of Dabigatran Concentration Using Finger Prick Dried Blood Spot Sample Collection

Frontiers in Pharmacology, 2021
Background and Purpose: Real-world laboratory monitoring of dabigatran activity is challenging. The purpose of the present study was to demonstrate the feasibility and accuracy of finger prick sampling with dried blood spot (fpDBS) cards in measuring the
Shin-Yi Lin, Shin-Yi Lin, Yu-Fong Peng, Chih-Fen Huang, Chih-Fen Huang, Ching-Hua Kuo, Sung-Chun Tang, Jiann-Shing Jeng   +7 more
doaj   +1 more source

Recanalization after cerebral venous thrombosis. A randomized controlled trial of the safety and efficacy of dabigatran etexilate versus dose-adjusted warfarin in patients with cerebral venous and dural sinus thrombosis

International Journal of Stroke, 2021
Background The effect of different anticoagulants on recanalization after cerebral venous thrombosis has not been studied in a randomized controlled trial.
J. Ferro, M. Bendszus, O. Jansen, J. Coutinho, F. Dentali, A. Kobayashi, D. Aguiar de Sousa, L. Neto, C. Miede, Jorge Caria, Holger Huisman, H. Diener   +11 more
semanticscholar   +1 more source

The Impact of ABCB1 and CES1 Polymorphisms on Dabigatran Pharmacokinetics in Healthy Chinese Subjects

Pharmacogenomics and Personalized Medicine, 2021
Dabigatran is a novel direct oral anticoagulant agent, whose plasma concentration is closely related to bleeding risk. Genetic polymorphisms can affect the level of plasma dabigatran.
Yue Liu, Chenguang Yang, Wenyuan Qi, Zuowei Pei, W. Xue, Huolan Zhu, Min Dong, Yingqiao Guo, Duanduan Cong, Fang Wang   +9 more
semanticscholar   +1 more source

The Dabigatran debate

Global Cardiology Science and Practice, 2014
In the June 2013 issue of this Journal, we described compelling evidence for the use of three novel anticoagulants, including Dabigatran, on the basis of recent large multi-centre trials.1 We acknowledged the approval of NOACs over warfarin in the ESC update and ACCP guidelines, and foresaw the greater usage of these newer, promising, therapies for ...
Kaba, Riyaz A, Ara, Farhana, Ward, David E, Emanuel, Subo   +3 more
openaire   +2 more sources

Dabigatran for Prevention of Stroke after Embolic Stroke of Undetermined Source

New England Journal of Medicine, 2019
Background Cryptogenic strokes constitute 20 to 30% of ischemic strokes, and most cryptogenic strokes are considered to be embolic and of undetermined source.
H. Diener, R. Sacco, D. Easton, C. Granger, R. Bernstein, S. Uchiyama, J. Kreuzer, Lisa Cronin, Daniel Cotton, Claudia Grauer, M. Brueckmann, M. Chernyatina, G. Donnan, J. Ferro, M. Grond, B. Kallmünzer, J. Krupiński, Byung‐Chul Lee, R. Lemmens, J. Masjuán, M. Odinak, J. Saver, P. Schellinger, D. Toni, K. Toyoda   +24 more
semanticscholar   +1 more source