Possibilities for monitoring the pharmacodynamics of dabigatran etexilate
The sensitivity and prognostic value of laboratory tests and methods for assessing pharmacodynamics in relation to the system of regulation of the aggregate state of blood after a single dose of dabigatran etexilate at a dosage of 150 mg were ...
M. A. Solovyev +4 more
doaj +1 more source
Physiologically-based pharmacokinetics modeling to investigate formulation factors influencing the generic substitution of dabigatran etexilate. [PDF]
Farhan N +9 more
europepmc +1 more source
Background: Vitamin K antagonists have been the treatment of choice in preventing thromboembolic events, but problems such as frequent dose adjustment and monitoring of coagulation status, including multiple drug and food interactions, make their use ...
Norbeck AO, Donaldson M
core +2 more sources
Pharmacokinetic modeling and simulation support for age- and weight-adjusted dosing of dabigatran etexilate in children with venous thromboembolism. [PDF]
Röshammar D +14 more
europepmc +1 more source
SummaryOral dabigatran etexilate is indicated for the prevention of stroke and systemic embolism in patients with atrial fibrillation (AF) in whom anticoagulation is appropriate.
Anuraag Kansal +6 more
core +1 more source
Comparison of the efficacy of rivaroxaban and dabigatran etexilate in preventing venous thrombosis after arthroplasty: A protocol of randomized controlled trial. [PDF]
Song R, Qu R, Wang Y, Zhou D, Zhang A.
europepmc +1 more source
Off-target effects of oral anticoagulants - vascular effects of vitamin K antagonist and non-vitamin K antagonist oral anticoagulant dabigatran etexilate. [PDF]
van Gorp RH +14 more
europepmc +1 more source
Expanding horizons of anticoagulant therapy: Dabigatran etexilate a novel oral anticoagulant [PDF]
Thrombo-embolic disease is a major challenging clinical problem associated with significant mortality and morbidity. Anticoagulation with the existing heparin products and vitamin K antagonist (VKA) anticoagulants are still the mainstay of management ...
Vieira, Alfven +4 more
core
New options with dabigatran etexilate in anticoagulant therapy
Lars Maegdefessel, Joshua M Spin, Junya Azuma, Philip S TsaoDepartment of Cardiovascular Medicine, Stanford University – School of Medicine, Stanford, CA, USAAbstract: Thrombosis, the localized clotting of blood, occurs in both the arterial and
Lars Maegdefessel +3 more
doaj
Pharmacokinetics and Safety of Dabigatran Etexilate after Single and Multiple Oral Doses in Healthy Chinese Subjects. [PDF]
Duan J +5 more
europepmc +1 more source

